Das Kishore, Dey Rohan, Nath Jyotiman, Das Anupam, Kakati Kaberi, Barman Geetanjali, Kakoti Lopamudra
Department of Head & Neck Surgery, Dr B Borooah Cancer Institute, Guwahati, Assam India.
Department of Radiation Oncology, Dr B Borooah Cancer Institute, Guwahati, Assam India.
Indian J Otolaryngol Head Neck Surg. 2024 Apr;76(2):1836-1840. doi: 10.1007/s12070-023-04423-8. Epub 2023 Dec 16.
This research investigates potential connections between radiological tumour thickness determined by CT scans and various pathological prognostic factors. These factors include pathological tumour thickness (pTT), pathological depth of invasion (DOI), and positive cervical nodal metastasis. This analysis focuses on cases of clinicoradiologically node-negative squamous cell carcinoma of the buccal mucosa.
Sixty-one previously untreated clinicoradiologically node-negative squamous cell carcinoma of buccal mucosa were included in the study. The radiological tumour thickness in the preoperative CT scans is correlated with other prognostic factors like pathological tumour thickness, DOI and presence or absence of neck node.
Sixty-one patients were included in the study with a median age of 54 years (Range 27-84). Forty-two patients (68.9%) were male, and 19 were females (31.1%). There was no statistically significant difference in mean values of rTT among patients with positive or negative post-operative nodal metastases. However, a significant correlation could be established with rTT to other potential prognostic factors.
Tumor thickness in preoperative CT scans can be used to predict post-operative prognostic factors in oral squamous cell carcinoma.
本研究调查了CT扫描确定的放射学肿瘤厚度与各种病理预后因素之间的潜在联系。这些因素包括病理肿瘤厚度（pTT）、病理浸润深度（DOI）和颈部淋巴结转移阳性。本分析聚焦于临床放射学检查淋巴结阴性的颊黏膜鳞状细胞癌病例。
61例先前未经治疗的临床放射学检查淋巴结阴性的颊黏膜鳞状细胞癌纳入本研究。术前CT扫描中的放射学肿瘤厚度与其他预后因素相关，如病理肿瘤厚度、DOI以及颈部淋巴结的有无。
61例患者纳入本研究，中位年龄54岁（范围27 - 84岁）。42例患者（68.9%）为男性，19例为女性（31.1%）。术后淋巴结转移阳性或阴性患者的rTT平均值无统计学显著差异。然而，rTT与其他潜在预后因素之间可建立显著相关性。
术前CT扫描中的肿瘤厚度可用于预测口腔鳞状细胞癌的术后预后因素。
