Departement of Oncology, Hanoi Medical University, Hanoi, Vietnam.
Departement of Breast Surgery, Vietnam National Cancer Hospital, Hanoi, Vietnam.
Med Arch. 2024;78(2):131-138. doi: 10.5455/medarh.2024.78.131-138.
Breast cancer is the most common malignancy and remains the first cause of death related to cancer among Vietnamese women, with an incidence of 21,555 cases in 2020. Most breast cancer patients present with invasive disease and relatively large tumor sizes. While oncoplastic surgery (OPS) are commonly applied in Western countries, data on Asian population remains relatively limited.
This study aims to assess the outcomes of level-2 oncoplastic techniques in breast-conserving surgeries at the Vietnam National Cancer Hospital.
From January 2017 to June 2021, a cohort of 257 breast cancer patients who underwent breast-conserving surgery with OPS techniques were examined. Surgical complications, cosmetic outcome, recurrence and survival rates were assessed.
The mean age was 47.6±9.4 years, most patients had breast cup sizes B and C. The mean tumor size upon pathological examination was 2.00 ± 0.74 cm. Only 7 cases required reoperation, resulting in a mastectomy rate of 1.17%. The overall complication rate was low at 11.46%, with 9 cases (3.56%) experiencing delayed complications. Cosmetic results were rated as "excellent" in 20.6% and "good" in 60.5%, with a statistically significant difference. The rates of local recurrence, regional recurrence, and distant metastasis at five years were 2.78%, 1.19%, and 2.36%, respectively.
The level 2 oncoplastic techniques had low complication rates, favorable oncological outcomes, and cosmetically satisfying results.
乳腺癌是最常见的恶性肿瘤，也是越南女性癌症相关死亡的首要原因，2020 年发病率为 21,555 例。大多数乳腺癌患者表现为浸润性疾病和相对较大的肿瘤大小。虽然肿瘤整形术（oncoplastic surgery，OPS）在西方国家得到广泛应用，但亚洲人群的数据仍然相对有限。
本研究旨在评估越南国家癌症医院保乳手术中 2 级肿瘤整形技术的结果。
从 2017 年 1 月至 2021 年 6 月，对 257 例接受 OPS 技术保乳手术的乳腺癌患者进行了评估。评估了手术并发症、美容效果、复发率和生存率。
平均年龄为 47.6±9.4 岁，大多数患者乳房罩杯大小为 B 和 C。病理检查平均肿瘤大小为 2.00 ± 0.74cm。仅 7 例需要再次手术，因此乳房切除术率为 1.17%。总并发症发生率较低，为 11.46%，其中 9 例（3.56%）发生迟发性并发症。美容效果评定为“优秀”的占 20.6%，“良好”的占 60.5%，差异有统计学意义。五年局部复发率、区域复发率和远处转移率分别为 2.78%、1.19%和 2.36%。
2 级肿瘤整形技术具有较低的并发症发生率、良好的肿瘤学结果和令人满意的美容效果。
