Domagala W, Koss L G
Virchows Arch B Cell Pathol Incl Mol Pathol. 1979 May 31;30(2):231-43. doi: 10.1007/BF02889105.
Surface configuration of mesothelial cells identified by light microscopy (LM) has been studied by scanning electron microscopy (SEM). It has been shown that mesothelial cells may have a variable SEM appearance. The surfaces of a small proportion of mesothelial cells are covered by regular microvilli (MV) and show openings of the pinocytotic vesicles. The surfaces of the majority of these cells are covered by vesicles or blebs. An intermediate population of mesothelial cells, i.e., cells displaying side-by-side blebs and MV, has also been observed. The latter cells no longer display pinocytotic vesicles. Occasional mesothelial cells have smooth surfaces. It has been shown by LM and transmission electron microscopy that cells with blebs are viable and capable of mitotic activity. It is concluded that mesothelial cells, detached from their epithelial setting, lose microvilli and pinocytotic vesicles and acquire surface blebs. The possible relationship between mesothelial cells and macrophages based on surface features has been discussed.
通过扫描电子显微镜（SEM）研究了用光镜（LM）鉴定的间皮细胞的表面形态。结果表明，间皮细胞的扫描电镜外观可能各不相同。一小部分间皮细胞的表面覆盖有规则的微绒毛（MV），并显示有吞饮小泡的开口。这些细胞大多数的表面覆盖有小泡或泡状突起。还观察到了中间类型的间皮细胞，即并排显示泡状突起和微绒毛的细胞。后一种细胞不再显示吞饮小泡。偶尔有间皮细胞表面光滑。光镜和透射电子显微镜显示，有泡状突起的细胞是活的，并且具有有丝分裂活性。得出的结论是，从其上皮环境中脱离的间皮细胞会失去微绒毛和吞饮小泡，并获得表面泡状突起。基于表面特征讨论了间皮细胞与巨噬细胞之间可能的关系。
