Li Xinying, Kang Jia-Xin, Liang Shasha, Long Xi-Hong, Ma Yan-Na, Chen Xuenian
College of Chemistry, Zhengzhou University, Zhengzhou, Henan 450001, China.
School of Chemistry and Chemical Engineering, Henan Key Laboratory of Boron Chemistry and Advanced Energy Materials, Henan Normal University, Xinxiang, Henan 453007, China.
Chem Commun (Camb). 2024 May 21;60(42):5486-5489. doi: 10.1039/d3cc06108f.
The reduction mechanism of aldehyde/ketones with M(BH) is not fully understood, even though the hydroboration mechanism of weak Lewis base borane complexes is known to involve a four-membered ring transition state. Herein, the reduction mechanism of M(BH) in aprotic solvents has been elucidated for a six-membered ring, in which hydride transfer to the C atom from the B atom, formation of an L·BH adduct, and disproportionation of (BH(OR)) borane are involved. The metal cations and solvents participate in and significantly influence the reaction procedure. We believe that this mechanistic study would provide a further reference for the application of M(BH) in organic reactions.
