Department of Obstetrics, University Hospital Zurich, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
Fetal Diagn Ther. 2024;51(4):365-376. doi: 10.1159/000538588. Epub 2024 Apr 17.
In fetal surgery, successful pain management is crucial for postoperative mobilization, prophylaxis of contractions, and fast recovery. This study analyzed patient's pain experience after open fetal spina bifida (fSB) repair in comparison to pain scores after the subsequent Caesarean section (C-section).
Data were collected with a questionnaire given to 91 women, who had fSB repair and then C-section at our center between 2019 and 2022. It comprised 12 questions covering different aspects of pain experience and satisfaction with pain therapy and was answered by 67 women after fSB repair and 53 after C-section. Postoperative pain was rated on a Likert scale from 0 (slight/rarely) to 100 (strongest/always). Outcomes after fSB repair were compared to those after C-section. Additionally, subgroup analysis compared outcomes of women with different pain levels (group 1-5) after fSB repair.
Compared to women after C-section women after fSB repair reported significantly higher maximum pain scores (MPS) (p = 0.03), higher sleep disturbance due to pain (p = 0.03), and sedation rates (p = 0.001) as side effect from pain therapy. No differences were found regarding feelings of insecurity (p = 0.20) or helplessness (p = 0.40), as well as involvement in (p = 0.3) and satisfaction with pain therapy (p = 0.5). Subgroup analysis revealed that women with higher MPS after fSB repair were significantly more often non-Caucasians (p = 0.003) and more often affected by pain while lying in bed (p = 0.007) and during mobilization (p = 0.005). Additionally, they reported higher rates of dizziness (p = 0.02) and lower satisfaction rates with pain therapy (p = 0.03). Postoperative complication rate did not differ among groups.
Although women after fSB repair reported higher MPS compared to after C-section, the current pain management was generally perceived as satisfactory.
在胎儿手术中,成功的疼痛管理对于术后活动、预防宫缩和快速康复至关重要。本研究分析了开放式胎儿脊柱裂(fSB)修复后患者的疼痛体验,并与随后剖宫产(C -section)后的疼痛评分进行了比较。
数据收集采用问卷形式,共调查了 91 名 2019 年至 2022 年期间在我院接受 fSB 修复和随后 C-section 的女性。问卷包含 12 个问题,涵盖疼痛体验的不同方面以及对疼痛治疗的满意度,共 67 名 fSB 修复后和 53 名 C-section 后女性进行了回答。术后疼痛采用 0(轻微/很少)至 100(最强/总是)的 Likert 量表进行评分。比较 fSB 修复后的结果与 C-section 后的结果。此外,还进行了亚组分析,比较了 fSB 修复后不同疼痛程度(组 1-5)女性的结果。
与 C-section 后女性相比,fSB 修复后女性报告的最大疼痛评分(MPS)更高(p = 0.03),睡眠因疼痛而受到干扰的程度更高(p = 0.03),镇静发生率更高(p = 0.001)。但在对疼痛治疗的不安全感(p = 0.20)或无助感(p = 0.40)、参与度(p = 0.3)和满意度(p = 0.5)方面无差异。亚组分析显示,fSB 修复后 MPS 较高的女性更常是非高加索人(p = 0.003),更常因卧床(p = 0.007)和活动时(p = 0.005)疼痛而感到不适。此外,她们报告头晕的发生率更高(p = 0.02),对疼痛治疗的满意度更低(p = 0.03)。各组术后并发症发生率无差异。
尽管 fSB 修复后女性的 MPS 高于 C-section 后女性,但目前的疼痛管理总体上被认为是令人满意的。