Lin Chun-Yi, Wu Yi-Lun, Chien Yi-Ling, Gau Susan Shur-Fen
Department of Psychiatry, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan.
Department of Psychiatry, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, 10002, Taiwan; Symphonic Yard Clinic, 2F., Building B, No. 218-2, Section 4, Zhong-Xiao East Road, Taipei, 106059, Taiwan.
J Formos Med Assoc. 2025 Feb;124(2):157-163. doi: 10.1016/j.jfma.2024.03.022. Epub 2024 Apr 4.
Quality of life (QoL) has been suggested as an indicator of outcomes in autistic adults. Factors associated with QoL in autistic individuals remain unclear. This study aims to examine the subjective QoL for autistic adults in Taiwan and investigate the determinants for different domains of QoL.
The study comprised 90 autistic adults (aged 26.9, SD 7.3; males, 80.9%). We used Taiwanese version of World Health Organization Quality of Life-BREF to measure QoL. Four domains of QoL were compared with 61 non-autistic controls, including physical, psychological, social, and environment. To identify the correlates of QoL domains, we assessed IQ, personality trait, family support, anxiety/depressive symptoms, autistic severity, and sensory symptoms by various questionnaires, and assessed their association with QoL by correlation analyses and model selection.
Our results showed that autistic adults reported lower QoL on the World Health Organization Quality of Life (WHOQOL)-BREF across all domains. QoL was significantly associated with autistic symptom severity, harm avoidance, family support, sensory symptoms, anxiety, and depression, but not intelligence. Model selections revealed male sex, poor paternal support, autism severity, depression, anxiety, and sensory symptoms were associated with specific QoL domains.
Findings supported lower QoL in autistic adults. Modifying the QoL correlates may improve life quality in autistic adults. Furthermore, our findings revealed the importance of sensory symptoms and paternal support in QoL of autistic adults, which was a novel finding in this population.
生活质量(QoL)已被提议作为自闭症成年人预后的一个指标。自闭症个体中与生活质量相关的因素仍不清楚。本研究旨在调查台湾自闭症成年人的主观生活质量,并探究生活质量不同领域的决定因素。
本研究纳入了90名自闭症成年人(年龄26.9岁,标准差7.3;男性占80.9%)。我们使用世界卫生组织生活质量简表台湾版来测量生活质量。将生活质量的四个领域与61名非自闭症对照者进行比较,包括身体、心理、社会和环境领域。为了确定生活质量领域的相关因素,我们通过各种问卷评估了智商、人格特质、家庭支持、焦虑/抑郁症状、自闭症严重程度和感觉症状,并通过相关分析和模型选择评估它们与生活质量的关联。
我们的结果显示,自闭症成年人在世界卫生组织生活质量(WHOQOL)简表的所有领域中报告的生活质量较低。生活质量与自闭症症状严重程度、回避伤害、家庭支持、感觉症状、焦虑和抑郁显著相关,但与智力无关。模型选择显示,男性、父亲支持不足、自闭症严重程度、抑郁、焦虑和感觉症状与特定的生活质量领域相关。
研究结果支持自闭症成年人生活质量较低。改变与生活质量相关的因素可能会改善自闭症成年人的生活质量。此外,我们的研究结果揭示了感觉症状和父亲支持在自闭症成年人生活质量中的重要性,这在该人群中是一个新发现。