Marit G, David B, Reiffers J, Broustet A
Bull Cancer. 1985;72(1):37-41.
Ten patients with acute myeloid leukaemia on failure or relapse were treated by Amsacrine and high-dose (12 g/m2) Cytosine Arabinosyl (phase II trial). Four patients achieved complete remission, over six months in one instance. Hematologic toxicity was important but extra-hematologic toxicity was mild. These two drugs could be used as induction or reinforcement treatment in acute myeloid leukaemia.
十例急性髓系白血病失败或复发患者接受了安吖啶和高剂量（12 g/m²）阿糖胞苷治疗（II期试验）。四名患者实现完全缓解，其中一例缓解持续超过六个月。血液学毒性较为严重，但血液外毒性较轻。这两种药物可用于急性髓系白血病的诱导或强化治疗。
