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成人急性淋巴细胞白血病的治疗

Treatment of acute lymphoblastic leukemia in adults.

作者信息

Barbui T, Bassan R, Chisesi T, Battista R, Cortelazzo S, Rodeghiero F, Capnist G, D'Emilio A, Viero P, Dini E

出版信息

Hematol Oncol. 1985 Jan-Mar;3(1):49-53. doi: 10.1002/hon.2900030107.

Abstract

Thirty-seven adult patients with acute lymphoblastic leukemia were treated with a protocol called HEAV'D including Adriamycin, Vincristine, L-Asparaginase, Cyclophosphamide and Dexamethasone. The complete remission rate was 70 per cent. The median duration of remission was more than 30 months. Patients with initial leukocyte count below 20 000/mmc experienced a longer remission (median not reached) than patients with a leukocyte count above 20 000/mmc (median 10 months).

摘要

37例成年急性淋巴细胞白血病患者接受了一种名为HEAV'D的方案治疗,该方案包括阿霉素、长春新碱、L-天冬酰胺酶、环磷酰胺和地塞米松。完全缓解率为70%。缓解期的中位数超过30个月。初始白细胞计数低于20000/mmc的患者缓解期更长(中位数未达到),高于白细胞计数高于20000/mmc的患者(中位数为10个月)。

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