Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg.
S Afr Fam Pract (2004). 2024 Feb 29;66(1):e1-e5. doi: 10.4102/safp.v66i1.5833.
Persistent challenges in addressing severe neonatal hyperbilirubinaemia in resource-constrained settings have led to ongoing and often unacceptable rates of morbidity, disability and mortality. These challenges stem from limitations such as inadequate, inefficient or financially inaccessible diagnostic and therapeutic options. However, over the past decade, noteworthy innovations have emerged to address some of these hurdles, and these innovations are increasingly poised for broader implementation. This review provides a concise summary of these novel, economically viable diagnostic solutions, encompassing point-of-care assays and smartphone applications, as well as treatment modalities, notably more effective phototherapy and filtered sunlight. These advancements hold promise and have the potential to meaningfully reduce the burden of neonatal hyperbilirubinaemia, signifying a promising shift in the landscape of neonatal healthcare.
在资源有限的情况下,解决严重新生儿高胆红素血症的持续挑战导致了持续存在且往往不可接受的发病率、残疾率和死亡率。这些挑战源于诊断和治疗选择不足、效率低下或无法负担等限制。然而,在过去十年中,出现了一些值得注意的创新,以解决其中的一些障碍,这些创新越来越有可能得到更广泛的实施。本综述简要总结了这些新颖的、经济可行的诊断解决方案,包括即时检测分析和智能手机应用程序,以及治疗方式,特别是更有效的光疗和过滤后的阳光。这些进展具有潜力,可以显著减轻新生儿高胆红素血症的负担,标志着新生儿保健领域的一个有希望的转变。