Munjal Ritika, Kyarikwal Reena, Sarkar Sayantan, Nag Probal, Vennapusa Sivaranjana Reddy, Mukhopadhyay Suman
Department of Chemistry, School of Basic Sciences, Indian Institute of Technology Indore, Khandwa road, Simrol, Indore 453552, India.
School of Chemistry, Indian Institute of Science Education and Research Thiruvananthapuram, Thiruvananthapuram 695551, India.
Inorg Chem. 2024 Apr 15;63(15):7089-7103. doi: 10.1021/acs.inorgchem.4c01177. Epub 2024 Apr 4.
The carbohydrazide-based gelation component N,N,N-(1,3,5-triazine-2,4,6-triyl)tris(benzene-1,3,5-tricarbohydrazide) () was synthesized and characterized using various spectroscopic tools. and trimesic acid () get self-assembled to form metallogel with Fe, specifically through various noncovalent interactions in a DMSO and HO mixture. The self-assembly shows remarkable specificity toward Fe(III) among different transition metal salts. It is pertinent to point out that the binding specificity for Fe can also be found in nature in the form of siderophores, as they are mainly involved in scavenging iron selectively from the surroundings. DFT studies have been used to investigate the possible interaction between the different components of the iron metallogel. To determine the selectivity of for iron, , along with trimesic acid, is used to interact with other metal ions, including Fe(III) ions, in a single system. The gelation components and selectively bind with iron(III), which leads to the formation of metallogel and gets separated as a discrete layer, leaving the other metal ions in the solution. Therefore, and together show iron-scavenging properties. This selective scavenging property is explored through FE-SEM, XPS, PXRD, IR, and ICP-AES analysis. The FE-SEM analysis shows a flower-petal-like morphology for the Fe(III) metallogel. The resemblance in the metallogel and metallogel obtained from the mixture of different metal salts is established through FE-SEM images and XPS analysis. The release of iron from the metallogel is achieved with the help of ascorbic acid, which converts Fe to Fe. In biological systems, iron also gets released similarly from siderophores. This is the first report where the synthesized gelation component molecule is capable of scavenging out iron in the form of metallogel and self-separating from the aqueous mixture in the presence of various other metal ions.
基于 carbohydrazide 的凝胶化组分 N,N,N-(1,3,5-三嗪-2,4,6-三基)三(苯-1,3,5-三碳酰肼)() 被合成，并使用各种光谱工具进行了表征。 和均苯三甲酸() 通过 DMSO 和 H₂O 混合物中的各种非共价相互作用自组装形成与 Fe 的金属凝胶。在不同的过渡金属盐中，这种自组装对 Fe(III) 表现出显著的特异性。值得指出的是，对 Fe 的结合特异性在自然界中也以铁载体的形式存在，因为它们主要参与从周围环境中选择性地清除铁。DFT 研究已用于研究铁金属凝胶不同组分之间可能的相互作用。为了确定对铁的选择性， 在单个系统中与均苯三甲酸一起用于与其他金属离子相互作用，包括 Fe(III) 离子。凝胶化组分 和 与铁(III) 选择性结合，导致形成金属凝胶并作为离散层分离，使其他金属离子留在溶液中。因此， 和 一起表现出铁清除特性。通过 FE-SEM、XPS、PXRD、IR 和 ICP-AES 分析探索了这种选择性清除特性。FE-SEM 分析显示 Fe(III) 金属凝胶具有花瓣状形态。通过 FE-SEM 图像和 XPS 分析确定了 金属凝胶与从不同金属盐混合物中获得的金属凝胶的相似性。金属凝胶中的铁通过抗坏血酸的作用释放，抗坏血酸将 Fe 转化为 Fe。在生物系统中，铁也以类似的方式从铁载体中释放出来。这是第一份报告，其中合成的凝胶化组分 分子能够以金属凝胶的形式清除铁，并在存在各种其他金属离子的情况下从水性混合物中自我分离。
