Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Am J Otolaryngol. 2024 Jul-Aug;45(4):104241. doi: 10.1016/j.amjoto.2024.104241. Epub 2024 Mar 27.
About 12.5 % of patients diagnosed with benign paroxysmal positional vertigo (BPPV), experience persistent BPPV where it is unknown why some BPPV cases are very refractory (vrBPPV) to treatment.
The primary objective was to investigate if patients with vrBPPV could be successfully treated with a mechanical rotation chair (MRC) adjusted to the exact vertical semicircular canal (SCC) angles of the individual patient. Secondary endpoint was to determine if inner ear anomalies were predominant in these patients.
This prospective clinical trial included 20 patients (main group) who underwent computed tomography (CT) with measurements of the bony island and the width between the SCC walls of the posterior leg of the lateral SCCs. The inter-SCC angles, the angles between the sagittal plane and the vertical SCCs were compared to the presumed mean standard angles of the SCCs. Of these, 14 patients (subgroup) underwent individualized treatment with the Rotundum® repositioning chair according to their measured SCC angles.
All measured SCC angles differed significantly (p < 0.05) from the presumed mean standard SCC angles, except the angle between the sagittal plane and the left posterior SCC (p-SCC). Three out of 14 patients experienced subjective and objective remission after treatment with this MRC. Six out of 14 patients experienced either subjective remission or objective remission.
Patients with vrBPPV have vertical SCC angles that differ significantly from the presumed mean standard SCC angles. Individualized treatment with this MRC successfully treated 21.4 % of the patients with vrBPPV and provided subjective relief for 42.9 %.
约 12.5%被诊断为良性阵发性位置性眩晕(BPPV)的患者会出现持续性 BPPV,而目前尚不清楚为什么有些 BPPV 病例对治疗非常抵抗(vrBPPV)。
主要目的是研究 vrBPPV 患者是否可以通过机械旋转椅(MRC)成功治疗,该 MRC 可根据个体患者的垂直半规管(SCC)的确切角度进行调整。次要终点是确定这些患者是否存在内耳异常。
这项前瞻性临床试验纳入了 20 名患者(主要组),他们接受了计算机断层扫描(CT)检查,对骨性岛和外侧 SCC 后肢 SCC 壁之间的宽度进行了测量。测量了 SCC 之间的角度,即矢状面与垂直 SCC 之间的角度,并与假定的 SCC 标准平均角度进行了比较。其中 14 名患者(亚组)根据其测量的 SCC 角度,采用 Rotundum®复位椅进行个体化治疗。
所有测量的 SCC 角度均与假定的标准 SCC 平均角度显著不同(p<0.05),除了矢状面与左侧后 SCC(p-SCC)之间的角度。14 名患者中有 3 名在接受这种 MRC 治疗后主观和客观缓解。14 名患者中有 6 名出现主观缓解或客观缓解。
vrBPPV 患者的 SCC 垂直角度与假定的标准 SCC 角度有显著差异。采用这种 MRC 进行个体化治疗成功治疗了 21.4%的 vrBPPV 患者,并为 42.9%的患者提供了主观缓解。