Department of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Rue Du Bugnon 44, Lausanne 1011, Switzerland.
Institute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, Bern 3012, Switzerland.
Immunol Allergy Clin North Am. 2024 May;44(2):197-204. doi: 10.1016/j.iac.2023.12.007. Epub 2024 Jan 12.
Edema, rings, exudates, furrows, and strictures (EREFS) represent the major endoscopic features of eosinophilic esophagitis (EoE). The Endoscopic Reference System (EREFS) grading system is easy to learn and apply during daily clinical practice in the diagnosis and follow-up of EoE patients. When endoscopy is performed by an EoE-experienced physician, the EREFS criteria will identify the majority of EoE patients. The EREFS score from the area of greatest involvement of the esophagus should be reported. The EREFS grading system was formally validated as an endoscopy score and several randomized placebo-controlled trials have shown responsiveness of the EREFS score to therapeutic interventions.
水肿、环、渗出物、皱襞和狭窄（EREFS）是嗜酸性食管炎（EoE）的主要内镜特征。内镜参考系统（EREFS）分级系统易于学习和应用，可用于 EoE 患者的诊断和随访。当 EoE 经验丰富的医生进行内镜检查时， EREFS 标准将识别大多数 EoE 患者。应报告食管受累最严重部位的 EREFS 评分。 EREFS 分级系统已被正式验证为内镜评分，多项随机安慰剂对照试验表明 EREFS 评分对治疗干预有反应。
