Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1198, New York, NY 10029, USA.
Department of Gastroenterology & Hepatology, Northwestern Feinberg School of Medicine, Digestive Health Center, 259 East Erie, Suite 1600, Chicago, IL 60611, USA.
Immunol Allergy Clin North Am. 2024 May;44(2):383-396. doi: 10.1016/j.iac.2024.01.009. Epub 2024 Feb 12.
Patients with non-eosinophilic esophagitis eosinophilic gastrointestinal diseases (non-EoE EGIDs) are prone to nutritional deficiencies due to food-avoidant behaviors, malabsorption, and high nutrition impact symptoms. Nutrient deficiencies correspond to the segment, depth, and extent of the gastrointestinal tract involved and can impact organs distant from the gut. Patients with non-EoE EGIDs are often atopic, and some appear to respond to dietary avoidance of specific food allergens. Tests to identify food triggers other than response to elimination diets are lacking. Dietary restriction therapy should be considered in such patients and is best implemented through a multidisciplinary approach to avoid nutritional complications.
非嗜酸性食管炎嗜酸细胞性胃肠病（非 EoE EGIDs）患者由于回避性行为、吸收不良和高营养影响症状而易发生营养缺乏。营养素缺乏与胃肠道受累的节段、深度和范围相对应，并可能影响远离肠道的器官。非 EoE EGIDs 患者通常为特应性，一些患者似乎对特定食物过敏原的饮食回避有反应。目前缺乏识别除消除饮食反应之外的食物触发因素的检测方法。对于此类患者应考虑饮食限制疗法，最好通过多学科方法来实施，以避免营养并发症。
