Department of Neurology, Yonsei University College of Medicine, Republic of Korea.
Department of Neurology, Yonsei University College of Medicine, Republic of Korea.
Neurol Clin. 2024 May;42(2):487-496. doi: 10.1016/j.ncl.2023.12.004. Epub 2024 Jan 12.
The prevalence of brain tumors in patients with headache is very low; however, 48% to 71% of patients with brain tumors experience headache. The clinical presentation of headache in brain tumors varies according to age; intracranial pressure; tumor location, type, and progression; headache history; and treatment. Brain tumor-associated headaches can be caused by local and distant traction on pain-sensitive cranial structures, mass effect caused by the enlarging tumor and cerebral edema, infarction, hemorrhage, hydrocephalus, and tumor secretion. This article reviews the current findings related to epidemiologic details, clinical manifestations, mechanisms, diagnostic approaches, and management of headache in association with brain tumors.
脑肿瘤患者头痛的患病率非常低；然而，48%至 71%的脑肿瘤患者会出现头痛。脑肿瘤头痛的临床表现因年龄、颅内压、肿瘤位置、类型和进展、头痛病史和治疗而异。脑肿瘤相关头痛可由疼痛敏感颅结构的局部和远处牵拉、肿瘤增大和脑水肿、梗死、出血、脑积水和肿瘤分泌引起。本文综述了与脑肿瘤相关头痛的流行病学细节、临床表现、机制、诊断方法和治疗的最新研究结果。
