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BMJ Case Rep. 2024 Apr 4;17(4):e257965. doi: 10.1136/bcr-2023-257965.
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本文引用的文献

1
Bacillus cereus Invasive Infections in Preterm Neonates: an Up-to-Date Review of the Literature.蜡样芽胞杆菌致早产儿侵袭性感染:文献复习的最新进展。
Clin Microbiol Rev. 2022 Apr 20;35(2):e0008821. doi: 10.1128/cmr.00088-21. Epub 2022 Feb 9.
2
Bacillus cereus: Epidemiology, Virulence Factors, and Host-Pathogen Interactions.蜡样芽胞杆菌:流行病学、毒力因子和宿主-病原体相互作用。
Trends Microbiol. 2021 May;29(5):458-471. doi: 10.1016/j.tim.2020.09.003. Epub 2020 Sep 28.
3
The Group: Species with Pathogenic Potential.群组:具有潜在致病性的物种。
Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.GPP3-0032-2018.
4
Identification and Containment of a Cluster of Two Infections in a Neonatal Intensive Care Unit.新生儿重症监护病房中两例感染聚集性病例的识别与控制
Can J Infect Dis Med Microbiol. 2019 Jan 20;2019:1506583. doi: 10.1155/2019/1506583. eCollection 2019.
5
Two unrelated episodes of Bacillus cereus bacteremia in a neonatal intensive care unit.新生儿重症监护病房内两例无关的蜡样芽孢杆菌菌血症病例。
Am J Infect Control. 2014 Jun;42(6):694-5. doi: 10.1016/j.ajic.2014.01.025. Epub 2014 Apr 13.
6
An outbreak of Bacillus cereus respiratory tract infections on a neonatal unit due to contaminated ventilator circuits.新生儿病房因呼吸机回路污染爆发蜡样芽孢杆菌呼吸道感染。
J Hosp Infect. 1999 Jan;41(1):19-22. doi: 10.1016/s0195-6701(99)90032-4.
7
Bacillus cereus pneumonia in premature neonates: a report of two cases.早产儿蜡样芽孢杆菌肺炎:两例报告
Pediatr Infect Dis J. 1993 Mar;12(3):251-3. doi: 10.1097/00006454-199303000-00019.
8
Severe systemic and pyogenic infections with Bacillus cereus.蜡样芽孢杆菌引起的严重全身性和化脓性感染。
Br Med J. 1977 Jun 25;1(6077):1628-9. doi: 10.1136/bmj.1.6077.1628.

新生儿:一例需要 ECMO 的先天性肺炎罕见病例。

Neonatal : an unusual case of congenital pneumonia requiring ECMO.

机构信息

Paediatric Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK

Paediatric Infectious Diseases, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

出版信息

BMJ Case Rep. 2024 Apr 4;17(4):e257965. doi: 10.1136/bcr-2023-257965.

DOI:10.1136/bcr-2023-257965
PMID:38575335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11002414/
Abstract

A term neonate presented with cyanosis from birth, with refractory hypoxaemia despite intubation, administration of 100% oxygen and inhaled nitric oxide. Structural congenital heart disease was excluded. He developed profuse pulmonary haemorrhage at 6 hours of life with worsening hypoxia and was transferred to a paediatric intensive care unit (PICU) for initiation of veno-venous extracorporeal membrane oxygenation (vvECMO). Endotracheal aspirates from both the birth hospital and the PICU were positive for , with all other investigations finding no alternative cause for his presentation. Of note, mother was a practising veterinarian raising another potential source of exposure to this pathogen. A full recovery occurred after a total of 5 days of vvECMO, 13 days of ventilation and 20 days of PICU stay.

摘要

一名新生儿出生时即出现发绀,尽管进行了插管、100%吸氧和吸入一氧化氮治疗,但仍存在难治性低氧血症。排除了结构性先天性心脏病。他在出生后 6 小时出现大量肺出血,缺氧情况恶化,并转至儿科重症监护病房(PICU)开始进行静脉-静脉体外膜肺氧合(vvECMO)治疗。出生医院和 PICU 的气管内吸出物均检测到 阳性,所有其他检查均未发现导致其出现这种情况的其他原因。值得注意的是,母亲是一名执业兽医,家中还有另一个可能接触这种病原体的潜在来源。在接受了总共 5 天的 vvECMO、13 天的通气和 20 天的 PICU 治疗后,患儿完全康复。