Paediatric Intensive Care Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK
Paediatric Infectious Diseases, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
BMJ Case Rep. 2024 Apr 4;17(4):e257965. doi: 10.1136/bcr-2023-257965.
A term neonate presented with cyanosis from birth, with refractory hypoxaemia despite intubation, administration of 100% oxygen and inhaled nitric oxide. Structural congenital heart disease was excluded. He developed profuse pulmonary haemorrhage at 6 hours of life with worsening hypoxia and was transferred to a paediatric intensive care unit (PICU) for initiation of veno-venous extracorporeal membrane oxygenation (vvECMO). Endotracheal aspirates from both the birth hospital and the PICU were positive for , with all other investigations finding no alternative cause for his presentation. Of note, mother was a practising veterinarian raising another potential source of exposure to this pathogen. A full recovery occurred after a total of 5 days of vvECMO, 13 days of ventilation and 20 days of PICU stay.
一名新生儿出生时即出现发绀,尽管进行了插管、100%吸氧和吸入一氧化氮治疗,但仍存在难治性低氧血症。排除了结构性先天性心脏病。他在出生后 6 小时出现大量肺出血,缺氧情况恶化,并转至儿科重症监护病房(PICU)开始进行静脉-静脉体外膜肺氧合(vvECMO)治疗。出生医院和 PICU 的气管内吸出物均检测到 阳性,所有其他检查均未发现导致其出现这种情况的其他原因。值得注意的是,母亲是一名执业兽医,家中还有另一个可能接触这种病原体的潜在来源。在接受了总共 5 天的 vvECMO、13 天的通气和 20 天的 PICU 治疗后,患儿完全康复。