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尿液培养的诊断管理。

Diagnostic Stewardship for Urine Cultures.

机构信息

Epidemiology and Public Health, University of Maryland School of Medicine, 10 S. Pine Street, Baltimore, MD 21201, USA.

Department of Practice and Science and Health Outcomes Research, University of Maryland School of Pharmacy, Baltimore, MD, USA.

出版信息

Infect Dis Clin North Am. 2024 Jun;38(2):255-266. doi: 10.1016/j.idc.2024.03.004. Epub 2024 Apr 4.

DOI:10.1016/j.idc.2024.03.004
PMID:38575490
Abstract

Urinary tract infections are among the most common infectious diagnoses in health care, but most urinary tract infections are diagnosed inappropriately in patients without signs or symptoms of infection. Asymptomatic bacteriuria leads to inappropriate antibiotic prescribing and negative downstream effects, including antimicrobial resistance, health care-associated infections, and adverse drug events. Diagnostic stewardship is the process of modifying the ordering, performing, or reporting of test results to improve clinical care. Diagnostic stewardship impacts the diagnostic pathway to decrease inappropriate detection and treatment of asymptomatic bacteriuria. This article reviews diagnostic stewardship methods and closes with a case study illustrating these principles in practice.

摘要

尿路感染是医疗保健中最常见的感染性诊断之一,但大多数尿路感染在没有感染迹象或症状的患者中被不恰当地诊断。无症状菌尿导致不适当的抗生素处方和负面的下游影响,包括抗菌药物耐药性、与医疗保健相关的感染和药物不良事件。诊断管理是指修改测试结果的订购、执行或报告以改善临床护理的过程。诊断管理会影响诊断途径,以减少无症状菌尿的不当检测和治疗。本文回顾了诊断管理方法,并以一个案例研究说明了这些原则在实践中的应用。

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1
Diagnostic Stewardship for Urine Cultures.尿液培养的诊断管理。
Infect Dis Clin North Am. 2024 Jun;38(2):255-266. doi: 10.1016/j.idc.2024.03.004. Epub 2024 Apr 4.
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Diagnosis and treatment of urinary tract infections across age groups.泌尿系统感染的诊断与治疗:各年龄段篇。
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Reducing Treatment of Asymptomatic Bacteriuria: What Works?减少无症状菌尿症的治疗:哪些方法有效?
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Urine culture guided antibiotic interventions: A pharmacist driven antimicrobial stewardship effort in the ED.尿培养指导下的抗生素干预:急诊科药师主导的抗菌药物管理工作
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Asymptomatic bacteriuria: Impact of an antimicrobial stewardship bundle to reduce unnecessary antibiotics in patients without urinary catheters.无症状菌尿:抗菌药物管理包对减少无导尿管患者不必要抗生素使用的影响。
Am J Health Syst Pharm. 2021 Aug 30;78(Supplement_3):S83-S87. doi: 10.1093/ajhp/zxab220.
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Antibiotic Stewardship Program Reduces Use of Urine Cultures and Antibiotics for Asymptomatic Bacteriuria.抗生素管理计划减少了无症状菌尿症尿液培养和抗生素的使用。
Am J Nurs. 2022 Nov 1;122(11):61. doi: 10.1097/01.NAJ.0000897148.99385.5e.
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Prevalence and predictors of urine culture contamination in primary care: A cross-sectional study.基层医疗中尿培养污染的流行情况及预测因素:一项横断面研究。
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Why is asymptomatic bacteriuria overtreated?: A tertiary care institutional survey of resident physicians.为什么无症状菌尿会被过度治疗?一项针对住院医师的三级医疗机构调查。
BMC Infect Dis. 2015 Jul 26;15:289. doi: 10.1186/s12879-015-1044-3.
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Urinary Tract Infections as a Continuum: Implications for Diagnostic and Antibiotic Stewardship.作为一个连续统一体的尿路感染:对诊断和抗生素管理的影响。
Clin Infect Dis. 2021 Apr 26;72(8):1339-1341. doi: 10.1093/cid/ciaa280.

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A personalized prediction model for distinguishing between asymptomatic bacteriuria and symptomatic urinary tract infections in patients with type 2 diabetes mellitus using machine learning.一种使用机器学习区分2型糖尿病患者无症状菌尿和有症状尿路感染的个性化预测模型。
Front Endocrinol (Lausanne). 2025 Aug 5;16:1593735. doi: 10.3389/fendo.2025.1593735. eCollection 2025.