Gong Xue, Zhou Jiangyuan, Chen Siyuan, Ji Yi
Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Pediatric Intensive Care Unit, Department of Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Heliyon. 2024 Mar 29;10(7):e28802. doi: 10.1016/j.heliyon.2024.e28802. eCollection 2024 Apr 15.
The coexistence of kaposiform hemangioendothelioma (KHE) and capillary malformation (CM) is quite rare, and few relevant studies can be found to confirm whether this phenomenon is accidental. We diagnosed and treated two such patients, revealing interesting phenomena associated with the development of vascular diseases. These cases offer the possibility that the coexistence of KHE and CM is not accidental and open up a new field of research related to pediatric vascular tumors and vascular malformations. Personalization and precision are required in the diagnosis and treatment of such patients, and the present findings provide a reliable theoretical and practical basis for further research on the pathogenesis and therapy of patients with multiple vascular diseases.
卡波西样血管内皮瘤(KHE)与毛细血管畸形(CM)并存的情况相当罕见,很少有相关研究能证实这种现象是否偶然。我们诊断并治疗了两名此类患者,发现了与血管疾病发展相关的有趣现象。这些病例提示KHE与CM并存并非偶然,为小儿血管肿瘤和血管畸形相关的新研究领域开辟了道路。对此类患者的诊断和治疗需要个性化和精准化,目前的研究结果为进一步研究多种血管疾病患者的发病机制和治疗提供了可靠的理论和实践基础。