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本文引用的文献

1
Risk assessment of venous thromboembolism in inflammatory bowel disease by inherited risk in a population-based incident cohort.基于人群发病队列的遗传性风险评估炎症性肠病的静脉血栓栓塞风险。
World J Gastroenterol. 2023 Oct 21;29(39):5494-5502. doi: 10.3748/wjg.v29.i39.5494.
2
Congenital thrombophilia in East-Asian venous thromboembolism population: a systematic review and meta-analysis.东亚静脉血栓栓塞人群中的先天性血栓形成倾向：一项系统评价和荟萃分析。
Res Pract Thromb Haemost. 2023 Aug 2;7(6):102157. doi: 10.1016/j.rpth.2023.102157. eCollection 2023 Aug.
3
International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease.国际炎症性肠病患者静脉和动脉血栓栓塞事件预防共识。
Nat Rev Gastroenterol Hepatol. 2021 Dec;18(12):857-873. doi: 10.1038/s41575-021-00492-8. Epub 2021 Aug 27.
4
Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease.炎症性肠病中血栓栓塞性疾病遗传风险的流行情况及其影响。
Gastroenterology. 2021 Feb;160(3):771-780.e4. doi: 10.1053/j.gastro.2020.10.019. Epub 2020 Oct 21.
5
Thromboprophylaxis for Hospitalized Patients with Inflammatory Bowel Disease-Are We There Yet?住院炎症性肠病患者的血栓预防——我们做到了吗？
J Clin Med. 2020 Aug 26;9(9):2753. doi: 10.3390/jcm9092753.
6
Acute Venous Thromboembolism Risk Highest Within 60 Days After Discharge From the Hospital in Patients With Inflammatory Bowel Diseases.炎症性肠病患者出院后 60 天内的急性静脉血栓栓塞风险最高。
Clin Gastroenterol Hepatol. 2020 May;18(5):1133-1141.e3. doi: 10.1016/j.cgh.2019.07.028. Epub 2019 Jul 20.
7
Thrombotic risk factors in Chinese Budd-Chiari syndrome patients. An observational study with a systematic review of the literature.中国布加综合征患者的血栓形成危险因素。一项观察性研究及文献系统评价。
Thromb Haemost. 2013 May;109(5):878-84. doi: 10.1160/TH12-10-0784. Epub 2013 Feb 28.
8
Factor V Leiden: is it the chief contributor to activated protein C resistance in Asian-Indian patients with deep vein thrombosis?凝血因子V莱顿突变：它是亚洲印度裔深静脉血栓形成患者中活化蛋白C抵抗的主要原因吗？
Clin Chim Acta. 2008 Jun;392(1-2):21-4. doi: 10.1016/j.cca.2008.02.018. Epub 2008 Feb 25.
9
Epidemiology of factor V Leiden: clinical implications.凝血因子V莱顿突变的流行病学：临床意义。
Semin Thromb Hemost. 1998;24(4):367-79. doi: 10.1055/s-2007-996025.
10
Prevalence of the factor V-Leiden mutation in four distinct American ethnic populations.
Am J Med Genet. 1997 Dec 19;73(3):334-6. doi: 10.1002/(sici)1096-8628(19971219)73:3<334::aid-ajmg20>3.0.co;2-j.

炎症性肠病相关静脉血栓栓塞的遗传风险分层：亚洲视角。

Genetic risk stratification of inflammatory bowel disease-associated venous thromboembolism: An Asian perspective.

机构信息

Division of Gastroenterology, Hepatology and Nutrition, Department of Paediatrics, Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore 119228, Singapore.

Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

出版信息

World J Gastroenterol. 2024 Mar 7;30(9):1250-1252. doi: 10.3748/wjg.v30.i9.1250.

DOI:10.3748/wjg.v30.i9.1250
PMID:38577175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10989499/
Abstract

The utilisation of polygenic scoring models may enhance the clinician's ability to risk stratify an inflammatory bowel disease patient's individual risk for venous thromboembolism (VTE) and guide the appropriate usage of VTE thromboprophylaxis, yet there is a need to validate such models in ethnically diverse populations.

摘要

多基因评分模型的应用可以提高临床医生对炎症性肠病患者个体静脉血栓栓塞（VTE）风险分层的能力，并指导 VTE 血栓预防的合理应用，但需要在不同种族人群中验证这些模型。