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与退行性颈椎手术住院时间延长相关的因素:来自加拿大脊柱结果和研究网络的队列分析。

Factors associated with increased length of stay in degenerative cervical spine surgery: a cohort analysis from the Canadian Spine Outcomes and Research Network.

机构信息

1Combined Neurosurgical and Orthopedic Spine Program, Department of Orthopedic Surgery, University of British Columbia, Vancouver, British Columbia.

2Canadian Spine Society, Markdale, Ontario.

出版信息

J Neurosurg Spine. 2024 Apr 5;41(1):46-55. doi: 10.3171/2024.1.SPINE231211. Print 2024 Jul 1.

Abstract

OBJECTIVE

Postoperative length of stay (LOS) significantly contributes to healthcare costs and resource utilization. The primary goal of this study was to identify patient, clinical, surgical, and institutional variables that influence LOS after elective surgery for degenerative conditions of the cervical spine. The secondary objectives were to examine the variability in LOS and institutional practices used to decrease LOS.

METHODS

This was a multicenter observational retrospective cohort study of patients enrolled in the Canadian Spine Outcomes and Research Network (CSORN) between January 2015 and October 2020 who underwent elective anterior cervical discectomy and fusion (ACDF) (1-3 levels) or posterior cervical fusion (PCF) (between C2 and T2) with/without decompression for degenerative conditions of the cervical spine. Prolonged LOS was defined as LOS greater than the median for the ACDF and PCF populations. The principal investigators at each participating CSORN healthcare institution completed a survey to capture institutional practices implemented to reduce postoperative LOS.

RESULTS

In total, 1228 patients were included (729 ACDF and 499 PCF patients). The median (IQR) LOS for ACDF and PCF were 1.0 (1.0) day and 5.0 (4.0) days, respectively. Predictors of prolonged LOS after ACDF were female sex, myelopathy diagnosis, lower baseline SF-12 mental component summary score, multilevel ACDF, and perioperative adverse events (AEs) (p < 0.05). Predictors of prolonged LOS after PCF were nonsmoking status, education less than high school, lower baseline numeric rating scale score for neck pain and EQ5D score, higher baseline Neck Disability Index score, and perioperative AEs (p < 0.05). Myelopathy did not significantly predict prolonged LOS within the PCF cohort after multivariate analysis. Of the 8 institutions (57.1%) with an enhanced recovery after surgery (ERAS) protocol or standardized protocol, only 3 reported using an ERAS protocol specific to patients undergoing ACDF or PCF.

CONCLUSIONS

Patient and clinical factors predictive of prolonged LOS after ACDF and PCF are highly variable, warranting individual consideration for possible mitigation. Perioperative AEs remained a consistent independent predictor of prolonged LOS in both cohorts, highlighting the importance of preventing intra- and postoperative complications.

摘要

目的

术后住院时间(LOS)显著影响医疗保健成本和资源利用。本研究的主要目标是确定影响颈椎退行性疾病择期手术患者 LOS 的患者、临床、手术和机构变量。次要目标是检查 LOS 的可变性和用于缩短 LOS 的机构实践。

方法

这是一项多中心回顾性队列研究,纳入了 2015 年 1 月至 2020 年 10 月期间在加拿大脊柱结果和研究网络(CSORN)登记的患者,这些患者接受了择期前路颈椎间盘切除术和融合术(1-3 个节段)或后路颈椎融合术(C2 至 T2 之间),伴或不伴颈椎退行性疾病的减压术。延长 LOS 定义为 ACDF 和 PCF 人群的 LOS 大于中位数。每个参与 CSORN 医疗机构的主要研究者完成了一项调查,以捕获用于减少术后 LOS 的机构实践。

结果

共纳入 1228 例患者(729 例行 ACDF,499 例行 PCF)。ACDF 和 PCF 的中位(IQR)LOS 分别为 1.0(1.0)天和 5.0(4.0)天。ACDF 术后 LOS 延长的预测因素包括女性、脊髓病诊断、较低的 SF-12 心理成分综合评分、多节段 ACDF 和围手术期不良事件(AE)(p<0.05)。PCF 术后 LOS 延长的预测因素包括不吸烟、教育程度低于高中、颈痛和 EQ5D 评分基线较低的数字评定量表评分、基线较高的颈部残疾指数评分和围手术期 AE(p<0.05)。多变量分析后,脊髓病在 PCF 队列中并未显著预测 LOS 延长。在 8 家(57.1%)有术后快速康复(ERAS)方案或标准化方案的机构中,只有 3 家报告使用了针对 ACDF 或 PCF 患者的特定 ERAS 方案。

结论

ACDF 和 PCF 术后 LOS 延长的预测因素因患者和临床因素而异,需要对可能的缓解措施进行个体化考虑。围手术期 AE 仍然是两个队列中 LOS 延长的一致独立预测因素,强调了预防围手术期并发症的重要性。

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