1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and.
2Faculty of Medicine, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan.
J Neurosurg Pediatr. 2024 Apr 5;34(1):75-83. doi: 10.3171/2024.1.PEDS23489. Print 2024 Jul 1.
The aim of this study was to delineate the clinical and socioeconomic variables associated with shunt revision in pediatric patients presenting to the emergency department (ED) with concerns of ventricular shunt malfunction.
A retrospective analysis of pediatric ED consultations for shunt malfunction over a 1-year period was conducted, examining clinical symptoms, radiographic findings, and socioeconomic variables. Sensitivities, specificities, and positive and negative predictive values were calculated for each presenting symptom collected. Logistic regression models were used to estimate the odds ratios for shunt revision based on these variables, and multivariate analyses were used to adjust for potential confounders.
Of the 271 ED visits from 137 patients, 19.2% resulted in shunt revision. Increased ventricle size on imaging (OR 11.38, p < 0.001), shunt site swelling (OR 9.04, p = 0.01), bradycardia (OR 7.08, p < 0.001), and lethargy (OR 5.77, p < 0.001) were significantly associated with shunt revision. Seizure-like activity was inversely related to revision needs (OR 0.24, p < 0.001). Patients with private or self-pay insurance were more likely to undergo revision compared with those with public insurance (p = 0.028). Multivariate analysis further confirmed the significant associations of increased ventricle size, lethargy, and bradycardia with shunt revision, while also revealing that seizure-like activity inversely affected the likelihood of revision. Patients with severe cognitive and language disabilities were more likely to be admitted to the hospital from the ED but were not more likely to undergo revision.
Clinical signs such as increased ventricle size, shunt site swelling, bradycardia, and lethargy may be strong predictors of the need for shunt revision in pediatric patients presenting to the ED with concerns of shunt malfunction. Socioeconomic factors play a less clear role in predicting shunt revision and admission from the ED; however, the nature of their influence is unclear. These findings can help inform clinical decision-making and optimize resource utilization in the ED.
本研究旨在描述与因脑室分流器故障而到急诊科就诊的儿科患者的分流器修订相关的临床和社会经济学变量。
对 1 年内因分流器故障而在急诊科就诊的儿科患者进行了回顾性分析,检查了临床症状、影像学结果和社会经济学变量。对收集到的每个就诊症状计算了灵敏度、特异性、阳性和阴性预测值。使用逻辑回归模型根据这些变量估计进行分流器修订的优势比,并进行多变量分析以调整潜在的混杂因素。
在 137 名患者的 271 次 ED 就诊中,19.2%需要进行分流器修订。影像学上脑室增大(OR 11.38,p<0.001)、分流器部位肿胀(OR 9.04,p=0.01)、心动过缓(OR 7.08,p<0.001)和嗜睡(OR 5.77,p<0.001)与分流器修订显著相关。癫痫样活动与修订需求呈负相关(OR 0.24,p<0.001)。与有公共保险的患者相比,私人或自付保险的患者更有可能接受修订(p=0.028)。多变量分析进一步证实了脑室增大、嗜睡和心动过缓与分流器修订的显著相关性,同时还表明癫痫样活动对修订可能性有相反影响。有严重认知和语言障碍的患者更有可能从急诊科住院,但不太可能进行修订。
临床体征,如脑室增大、分流器部位肿胀、心动过缓和嗜睡,可能是儿科患者因分流器故障到急诊科就诊时需要进行分流器修订的有力预测指标。社会经济学因素在预测从急诊科入院和进行分流器修订方面的作用较小;然而,其影响的性质尚不清楚。这些发现可以帮助指导临床决策并优化急诊科的资源利用。