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儿童耳内镜钛质听骨成形术后的长期疗效:单中心经验。

Long-term outcomes following pediatric endoscopic titanium ossiculoplasty: A single-institution experience.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2024 Apr;179:111938. doi: 10.1016/j.ijporl.2024.111938. Epub 2024 Apr 1.

Abstract

INTRODUCTION

Endoscopic ossicular chain reconstruction (OCR) in adults has demonstrated equivalent outcomes to the traditional microscopic approach. Less data exist on endoscopic OCR outcomes in children, who have unique considerations including a smaller transcanal corridor and variable pathology. The purpose of this study was to investigate surgical and audiometric outcomes in children undergoing fully endoscopic and endoscopic-assisted OCR in both the short and long-term.

METHODS

Retrospective review of all children (<17 years) who underwent endoscopic OCR at one tertiary care center between 2017 and 2021. Children undergoing primary and revision endoscopic OCR with either partial (PORP) and total ossicular reconstruction prostheses (TORP) were included. Children undergoing surgery for juvenile otosclerosis or congenital stapes fixation, or any child receiving a stapes prosthesis were excluded. Primary outcome measures were post-operative change in 4 frequency (500 Hz, 1, 2, 4 KHz) air conduction pure tone average (AC PTA) and change in air-bone gap (ABG). Secondary measures included need for readmission and/or revision surgery, complication rate, and surgery duration.

RESULTS

Seventeen patients met inclusion criteria. Average age was 11.3 years (range, 5-17 years); 14 were male. A variety of fixed length, titanium total and partial prostheses were used. The most common prosthesis length was 2 mm (range 2-5 mm), and there were no intra- or perioperative complications. Mean long-term follow-up was 2.6 years. Most common pathology was congenital cholesteatoma (11/17, 64%), followed by chronic otitis media with tympanic membrane perforation (5/17, 29.4%), and extruded prosthesis (1/17, 5.9%). Intraoperatively, the most common finding was incus erosion (10/17, 58.8%), followed by malleus erosion (6/17, 35.3%), stapes erosion (4/17, 23.5%), and stapes absence (4/17, 23.5%). Eight children (47%) were reconstructed with PORPs, and 9 children (52.9%) were reconstructed with TORPs. Average ABG improved from 36.8 dB preoperatively to 19.9 dB postoperatively in the short-term and remained stable at 19.5 dB in the long-term. Average short-term ABG improvement was 4.2 dB for PORPs and 18 dB for TORPs. In the long-term, average ABG improved by 2.3 dB in PORPs and 13.4 dB in TORPs. PORPs had higher rates of ABG closure and lower AC PTAs than TORPs in the long-term.

DISCUSSION

Endoscopic ossiculoplasty is a viable option in children presenting with ossicular erosion from various causes. Audiometric improvement following endoscopic partial and total ossicular reconstruction remains stable over time, with a preference towards partial in the long-term, and mirrors published outcomes for microscopic surgery.

摘要

介绍

成人内镜听骨链重建(OCR)已证明与传统显微镜方法具有等效的结果。在儿童中,内镜 OCR 的结果数据较少,因为儿童具有独特的考虑因素,包括更小的经耳道通道和不同的病变。本研究的目的是调查在一家三级护理中心接受完全内镜和内镜辅助 OCR 的儿童的手术和听力结果,包括短期和长期的结果。

方法

回顾性分析了 2017 年至 2021 年期间在一家三级护理中心接受内镜 OCR 的所有儿童(<17 岁)。包括接受原发性和修正性内镜 OCR 的儿童,使用部分(PORP)和全听骨重建假体(TORP)。排除接受青少年耳硬化症或先天性镫骨固定手术或任何儿童接受镫骨假体的儿童。主要的测量结果是术后 4 个频率(500 Hz、1、2、4 kHz)空气传导纯音平均值(AC PTA)的变化和气骨间隙(ABG)的变化。次要措施包括需要再次入院和/或修正手术、并发症发生率和手术持续时间。

结果

17 名患者符合纳入标准。平均年龄为 11.3 岁(范围 5-17 岁);14 名男性。使用了各种固定长度的钛全和部分假体。最常见的假体长度为 2mm(范围 2-5mm),无术中或围手术期并发症。平均长期随访时间为 2.6 年。最常见的病理是先天性胆脂瘤(11/17,64%),其次是慢性中耳炎伴鼓膜穿孔(5/17,29.4%)和挤出的假体(1/17,5.9%)。术中最常见的发现是砧骨侵蚀(10/17,58.8%),其次是锤骨侵蚀(6/17,35.3%)、镫骨侵蚀(4/17,23.5%)和镫骨缺失(4/17,23.5%)。8 名儿童(47%)接受 PORP 重建,9 名儿童(52.9%)接受 TORP 重建。ABG 在短期从术前的 36.8dB 改善到术后的 19.9dB,长期稳定在 19.5dB。PORP 的短期 ABG 改善平均值为 4.2dB,TORP 的短期 ABG 改善平均值为 18dB。长期来看,PORP 的 ABG 改善平均值为 2.3dB,TORP 的 ABG 改善平均值为 13.4dB。PORP 在长期的 ABG 关闭率和 AC PTA 均高于 TORP。

讨论

内镜听骨链重建术是一种可行的选择,适用于各种原因导致的听骨侵蚀的儿童。内镜部分和全听骨重建后的听力改善在长期内保持稳定,长期来看,更倾向于使用部分重建,这与显微镜手术的结果相吻合。

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