链接仍缺失：重新探讨 RNA 作为染色质相关蛋白的指导物的作用。

The links are still missing: Revisiting the role of RNA as a guide for chromatin-associated proteins.

机构信息

Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.

出版信息

Mol Cell. 2024 Apr 4;84(7):1178-1179. doi: 10.1016/j.molcel.2024.03.005.

DOI:10.1016/j.molcel.2024.03.005

Abstract

A new study in Molecular Cell by Guo et al. and two studies in Cell Reports by Healy et al. and by Hall Hickman and Jenner show how PRC2 and other chromatin regulators do not appear to bind RNA in vivo, challenging the importance of RNA for their function.

摘要

郭等人在《分子细胞》上的一项新研究，以及希利等人和霍尔·希克曼和詹纳在《细胞报告》上的两项研究表明，PRC2 和其他染色质调节剂在体内似乎不与 RNA 结合，这对它们功能的重要性提出了挑战。