Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK
Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
BMJ Open. 2024 Apr 5;14(4):e076451. doi: 10.1136/bmjopen-2023-076451.
To assess the effect of the COVID-19 pandemic on people experiencing incarceration (PEI), focusing particularly on clinical outcomes compared with the general population.
Systematic review with narrative synthesis in accordance with the Centre for Reviews and Dissemination's good practice guidelines.
Medline, Social Policy and Practice, Criminology Connection, ASSIA, EMBASE, SCOPUS, Web Of Science, CINAHL, Cochrane Library, Cochrane COVID-19 reviews, COVID-19 Evidence Reviews and L*OVE COVID-19 Evidence databases were searched up to 21 October 2022.
We included studies presenting data specific to adults ≥18 years experiencing incarceration, with exposure to SARS-CoV-2 infection. All studies with a comparison group, regardless of study design and country were included. Studies with no comparison group data or not measuring clinical outcomes/health inequalities were excluded. Studies focussing on detained migrants, forensic hospitals, prison staff and those not in English were also excluded.
Two reviewers extracted data and assessed risk of bias. Data underwent narrative synthesis using a framework analysis based on the objectives, for infection rates, testing, hospitalisation, mortality, vaccine uptake rates and mental health outcomes. There was no scope for meta-analysis, due to the heterogeneity of evidence available.
4516 references were exported from the databases and grey literature searched, of which 55 met the inclusion criteria. Most were from the USA and were retrospective analyses. Compared with the general population, PEI were usually found to have higher rates of SARS-CoV-2 infection and poorer clinical outcomes. Conflicting data were found regarding vaccine uptake and testing rates compared with the general population. The mental health of PEI declined during the pandemic. Certain subgroups were more adversely affected by the COVID-19 pandemic, such as ethnic minorities and older PEI.
PEI have poorer COVID-19 clinical outcomes than the general public, as shown by largely low-quality heterogenous evidence. Further high-quality research of continuing clinical outcomes and appropriate mitigating interventions is required to assess downstream effects of the pandemic on PEI. However, performing such research in the context of incarceration facilities is highly complex and potentially challenging. Prioritisation of resources for this vulnerable group should be a focus of national policy in the event of future pandemics.
CRD42022296968.
评估 COVID-19 大流行对被监禁者(PEI)的影响,重点关注与普通人群相比的临床结果。
根据中心的审查和传播的良好实践指南进行系统评价和叙述性综合。
检索了 Medline、社会政策与实践、犯罪学连接、ASSIA、EMBASE、SCOPUS、Web Of Science、CINAHL、Cochrane 图书馆、Cochrane COVID-19 评论、COVID-19 证据评论和 L*OVE COVID-19 证据数据库,截至 2022 年 10 月 21 日。
我们纳入了专门针对≥18 岁的经历监禁的成年人的数据,并接触了 SARS-CoV-2 感染的研究。所有具有对照组的研究,无论研究设计和国家如何,均被纳入。没有对照组数据或不测量临床结果/健康不平等的研究被排除在外。研究重点是被拘留的移民、法医医院、监狱工作人员和非英语人士的研究也被排除在外。
两名审查员提取数据并评估偏倚风险。使用基于目标的框架分析对数据进行叙述性综合,该分析基于感染率、检测、住院、死亡率、疫苗接种率和心理健康结果。由于现有证据的异质性,不进行荟萃分析。
从数据库和灰色文献中检索到 4516 篇参考文献,其中 55 篇符合纳入标准。大多数来自美国,是回顾性分析。与普通人群相比,PEI 通常被发现 SARS-CoV-2 感染率较高,临床结果较差。与普通人群相比,关于疫苗接种率和检测率的数据存在冲突。PEI 的心理健康在大流行期间下降。某些亚组受到 COVID-19 大流行的影响更大,例如少数民族和年龄较大的 PEI。
PEI 的 COVID-19 临床结果比普通公众差,这主要是由低质量的异质证据表明的。需要进一步进行高质量的研究,以评估大流行对 PEI 的临床结果和适当的缓解干预措施的后续影响。然而,在监禁设施的背景下进行这种研究非常复杂,可能具有挑战性。在未来发生大流行时,应优先考虑为这一弱势群体提供资源。
PROSPERO 注册号:CRD42022296968。