Bahl Amit, Mielke Nicholas, Gibson Steven Matthew, George Julie
William Beaumont Hospitals Corp, Royal Oak, MI, USA.
Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
J Infect Prev. 2024 May;25(3):73-81. doi: 10.1177/17571774241232063. Epub 2024 Feb 8.
Unscheduled dressing changes for central venous lines (CVLs) have been shown to increase the risk of bloodstream infections.
The objective of this study is to determine if the use of an innovative dressing change kit reduces the rate of unscheduled dressing changes.
This pre-post interventional study took place at a large, academic, tertiary care center in metro Detroit, Michigan, the United States. We assessed the impact of the interventional dressing change procedure kit on the rate of unscheduled dressing changes for adult patients who underwent placement of a CVL inclusive of a central catheter, peripherally inserted central catheter, or hemodialysis catheter. Data was collected for the pre-intervention cohort through electronic health records (EHRs), while data for the post-intervention cohort were collected by direct observation by trained research staff in combination with EHR data. The primary outcome was the rate of unscheduled dressing changes. Secondary outcomes included rate of unscheduled dressing changes based on admission floor type, etiology of unscheduled dressing changes, and central line-associated bloodstream infections (CLABSIs).
The study included a convenience sample of 1548 CVLs placed between May 2018 and June 2022 with a matched analysis including 488 catheters in each of the pre- and post-intervention groups. The results showed that the unadjusted rate of unscheduled dressing evaluations was significantly reduced from the pre-intervention group (0.21 per day) to the post-intervention group (0.13 per day) ( < .001). The adjusted rate ratio demonstrated the same trend at 1.00 pre- and 0.60 post-intervention ( < .001). Stratifying the analysis based on the highest level of care showed that the intervention was effective in reducing the unadjusted rate of unscheduled dressing evaluations for both the advanced and regular medical floor subgroups pre- to post-intervention; the advanced subgroup had an reduction from 0.22 to 0.15 per day ( = .001), while the regular medical floor subgroup had a reduction from 0.21 to 0.09 per day ( < .001). CLABSIs were similar in both groups (0.6% vs 0.8%; = 1.00) in pre- and post-intervention groups, respectively.
Procedural kits for central line dressing changes are effective in reducing unscheduled dressing changes and may have a role in reducing CLABSI. Further studies assessing the impact of dressing change kits on cost, procedural compliance, and the precise impact on CLABSI are needed.
中心静脉导管(CVL)的非计划换药已被证明会增加血流感染的风险。
本研究的目的是确定使用创新的换药套件是否能降低非计划换药的发生率。
这项干预前后的研究在美国密歇根州底特律市的一家大型学术三级护理中心进行。我们评估了干预性换药程序套件对接受CVL置入的成年患者(包括中心静脉导管、外周静脉置入中心静脉导管或血液透析导管)非计划换药发生率的影响。干预前队列的数据通过电子健康记录(EHR)收集,而干预后队列的数据由经过培训的研究人员直接观察并结合EHR数据收集。主要结局是非计划换药的发生率。次要结局包括基于入院楼层类型的非计划换药发生率、非计划换药的病因以及中心静脉导管相关血流感染(CLABSI)。
该研究纳入了2018年5月至2022年6月期间置入的1548根CVL的便利样本,进行匹配分析,干预前组和干预后组各有488根导管。结果显示,非计划换药评估的未调整发生率从干预前组(每天0.21次)显著降低至干预后组(每天0.13次)(<0.001)。调整后的发生率比值在干预前为1.00,干预后为0.60,显示出相同趋势(<0.001)。根据最高护理级别进行分层分析表明,干预在降低干预前后高级医疗楼层亚组和普通医疗楼层亚组的非计划换药评估未调整发生率方面均有效;高级亚组从每天0.22次降至0.15次(P = 0.001),而普通医疗楼层亚组从每天0.21次降至0.09次(<0.001)。干预前组和干预后组的CLABSI发生率相似(分别为0.6%和0.8%;P = 1.00)。
中心静脉导管换药的程序套件在减少非计划换药方面有效,可能在降低CLABSI方面发挥作用。需要进一步研究评估换药套件对成本、程序依从性以及对CLABSI的确切影响。