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Asian Bioeth Rev. 2023 Nov 29;16(2):205-221. doi: 10.1007/s41649-023-00268-z. eCollection 2024 Apr.
2
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J Assist Reprod Genet. 2022 Jul;39(7):1497-1500. doi: 10.1007/s10815-022-02526-9. Epub 2022 Jun 2.
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本文引用的文献

1
When elective egg freezers become egg donors: practical and ethical issues.当选择冻卵的女性成为捐卵者:实际问题与伦理问题。
Reprod Biomed Online. 2023 Jul;47(1):151-156. doi: 10.1016/j.rbmo.2023.03.019. Epub 2023 Apr 2.
2
Elective egg freezers' disposition decisions: a qualitative study.择期冻卵者的处置决策:一项定性研究。
Fertil Steril. 2023 Jul;120(1):145-160. doi: 10.1016/j.fertnstert.2023.02.022. Epub 2023 Apr 7.
3
Post-procedure counseling is recommended for disposal, export, and donation of unused frozen eggs (vitrified oocyte) for research or teaching/training.对于未使用的冷冻卵子(玻璃化卵母细胞)用于研究或教学/培训的处置、出口和捐赠,建议进行术后咨询。
J Assist Reprod Genet. 2022 Nov;39(11):2681-2683. doi: 10.1007/s10815-022-02630-w. Epub 2022 Oct 5.
4
Singapore needs to update regulation of frozen egg donation after permitting social egg freezing.新加坡在允许社会冻卵后,需要更新对冷冻卵子捐赠的监管规定。
J Assist Reprod Genet. 2022 Jul;39(7):1497-1500. doi: 10.1007/s10815-022-02526-9. Epub 2022 Jun 2.
5
Disposition preferences in oocyte preservation patients.卵母细胞保存患者的处置偏好。
J Assist Reprod Genet. 2022 Jul;39(7):1619-1624. doi: 10.1007/s10815-022-02518-9. Epub 2022 May 19.
6
Good practice recommendations for information provision for those involved in reproductive donation.为参与生殖捐赠者提供信息的良好实践建议。
Hum Reprod Open. 2022 Feb 16;2022(1):hoac001. doi: 10.1093/hropen/hoac001. eCollection 2022.
7
Women Electing Oocyte Cryopreservation: Characteristics, Information Sources, and Oocyte Disposition: A Systematic Review.选择卵母细胞冷冻保存的女性:特征、信息来源和卵母细胞处理:系统评价。
J Midwifery Womens Health. 2022 Mar;67(2):178-201. doi: 10.1111/jmwh.13332. Epub 2022 Feb 13.
8
Underground Gamete Donation in Sunni Muslim Patients.Sunni 穆斯林患者的地下配子捐赠。
J Relig Health. 2022 Aug;61(4):2905-2926. doi: 10.1007/s10943-021-01440-1. Epub 2021 Oct 18.
9
Disposition intentions of elective egg freezers toward their surplus frozen oocytes: a systematic review and meta-analysis.选择性卵子冷冻者对其剩余冷冻卵母细胞的处置意向:一项系统评价和荟萃分析
Fertil Steril. 2021 Dec;116(6):1601-1619. doi: 10.1016/j.fertnstert.2021.07.1195. Epub 2021 Aug 25.
10
Guidance regarding gamete and embryo donation.配子和胚胎捐赠指导。
Fertil Steril. 2021 Jun;115(6):1395-1410. doi: 10.1016/j.fertnstert.2021.01.045. Epub 2021 Apr 8.

为考虑捐赠未使用的剩余冷冻卵子用于生育治疗的选择性卵子冷冻患者提供咨询。

Counseling Elective Egg Freezing Patients considering Donation of Unused Surplus Frozen Eggs for Fertility Treatment.

作者信息

Chin Alexis Heng Boon, Nguma Jean-Didier Bosenge, Nkurunziza Charles, Sun Ningyu, Tong Guoqing

机构信息

Singapore Fertility and IVF Consultancy Pvt Ltd., Singapore.

Department of Obstetrics and Gynecology, Kisangani University Hospital, Kisangani, Democratic Republic of the Congo.

出版信息

Asian Bioeth Rev. 2023 Nov 29;16(2):205-221. doi: 10.1007/s41649-023-00268-z. eCollection 2024 Apr.

DOI:10.1007/s41649-023-00268-z
PMID:38586571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10994886/
Abstract

The majority of women who freeze their eggs for non-medical or social reasons, commonly referred to as elective egg freezing (EEF), do not eventually utilize their frozen eggs. This would result in an accumulated surplus of unused frozen eggs in fertility clinics worldwide, which represents a promising source of donation to infertile women undergoing IVF treatment. Rigorous and comprehensive counseling is needed, because the process of donating one's unused surplus frozen eggs involves complex decision-making. Prospective EEF donors can be broadly categorized into those who have achieved motherhood and those who remained childless and have given up on motherhood aspirations. A two-step systematic counseling protocol is proposed. Firstly, it is imperative to verify and ensure that these women do not want to conceive any children with their surplus frozen eggs before proceeding with further counseling and signing of consent forms. Secondly, various motivating and dissuading factors in the donation of unused surplus frozen eggs should then be comprehensively discussed with egg freezers to facilitate informed decision-making. Key motivating factors for donation include reciprocity in wanting to share the joys of motherhood among egg freezers who already have children, goodwill to help others in need, and avoiding the wastage of surplus frozen eggs after expending so much money, time, and effort. Key dissuading factors include fear of accidental incest between natural and unknown donor-conceived offspring, as well as apprehension of unexpected future contact with unknown donor-conceived offspring due to either donor anonymity being abolished in their jurisdiction or widespread consumer DNA testing.

摘要

大多数因非医学或社会原因冷冻卵子的女性,通常称为选择性卵子冷冻(EEF),最终并不会使用她们冷冻的卵子。这将导致全球生育诊所中积累大量未使用的冷冻卵子过剩,这是一个有前景的捐赠来源,可用于接受体外受精(IVF)治疗的不孕女性。需要进行严格而全面的咨询,因为捐赠自己未使用的过剩冷冻卵子的过程涉及复杂的决策。未来的EEF捐赠者大致可分为已实现母亲身份的人和仍未生育且已放弃生育愿望的人。本文提出了一个两步系统咨询方案。首先,在进行进一步咨询和签署同意书之前,必须核实并确保这些女性不想用她们过剩的冷冻卵子孕育任何孩子。其次,然后应与卵子冷冻者全面讨论捐赠未使用的过剩冷冻卵子的各种激励和劝阻因素,以促进明智的决策。捐赠的关键激励因素包括希望在已有孩子的卵子冷冻者中分享为人母的喜悦的互惠心理、帮助有需要的人的善意,以及避免在花费了大量金钱、时间和精力后浪费过剩的冷冻卵子。关键的劝阻因素包括担心自然受孕和未知捐赠者受孕的后代之间发生意外乱伦,以及由于其所在司法管辖区废除捐赠者匿名制或广泛的消费者DNA检测而担心未来与未知捐赠者受孕的后代意外接触。