Salvati F, Pupillo M
Minerva Med. 1985 Apr 28;76(17-18):841-6.
A high incidence of hereditary blood anomalies (particularly Pelger-Huët's congenital granulocytic anomaly and Lepore haemoglobinopathy) is reported in the people of the Sangro Valley (Abruzzo, South Italy). The clinical, haematological, genetic and demographic implications of the high incidence of these pathologies are discussed.
据报道,桑格罗山谷(意大利南部阿布鲁佐)的人群中遗传性血液异常(尤其是佩尔格-许特先天性粒细胞异常和 Lepore 血红蛋白病)的发病率很高。本文讨论了这些病症高发病率的临床、血液学、遗传学和人口统计学意义。