Department of Maxillofacial Surgery, Dubrava University Hospital, University of Zagreb School of Medicine, Zagreb, Croatia.
Department of Otorhinolaryngology and Maxillofacial Surgery, General Hospital Zadar, Zadar, Croatia.
Head Neck. 2024 Jun;46(6):1380-1389. doi: 10.1002/hed.27768. Epub 2024 Apr 8.
Data from patients with post-ablative dural defects reconstructed using a free temporalis muscle fascia graft (FTFG) after resection of anterior or central skull base tumors were retrospectively analyzed.
The primary predictor and outcome variables were the reconstructive methods for dural repair and postoperative cerebrospinal fluid (CSF) leakage rate, respectively.
Eighty patients were included, and 94 postoperative dural reconstructions were performed using FTFG. The postoperative CSF leakage rate was 3.19%. The postoperative CSF leakage rates did not significantly differ between open and endonasal endoscopic surgeries (1.92% vs. 4.88%; p > 0.05). In cases completed using the endonasal endoscopic approach, the postoperative CSF leakage rate was significantly associated with the intraoperative CSF leak flow (p < 0.05).
Post-ablative dural defect reconstruction using FTFG resulted in low postoperative CSF leakage and complication rates comparable to those of free fascia lata graft from available literature.
回顾性分析了切除前颅底或中颅底肿瘤后使用游离颞肌筋膜移植物（FTFG）修复术后硬脑膜缺损患者的数据。
主要预测变量和结局变量分别为硬脑膜修复的重建方法和术后脑脊液（CSF）漏率。
共纳入 80 例患者，94 例术后硬脑膜缺损采用 FTFG 修复。术后 CSF 漏率为 3.19%。开放性和经鼻内镜手术的术后 CSF 漏率无显著差异（1.92% vs. 4.88%；p>0.05）。在经鼻内镜手术完成的病例中，术后 CSF 漏率与术中 CSF 漏流量显著相关（p<0.05）。
使用 FTFG 修复硬脑膜缺损术后 CSF 漏和并发症发生率低，与游离阔筋膜移植物的文献报道结果相当。
