Médico General, Universidad de Antioquia, Medellín, Colombia.
Gerente en Sistemas de Información en Salud, GRAEPIC (Grupo Académico de Epidemiología Clínica), Universidad de Antioquia, Medellín, Colombia.
Rev Esp Anestesiol Reanim (Engl Ed). 2024 May;71(5):394-402. doi: 10.1016/j.redare.2024.04.001. Epub 2024 Apr 6.
To identify the first symptoms and signs of patients with suspected infection or sepsis and their association with the composite outcome of admission to the Intensive Care Unit (ICU) or mortality.
Prospective cohort study between June 2019 and March 2020.
Hospital Universitario San Vicente Fundación, Colombia.
Over 18 years of age with suspicion or confirmation of sepsis, which required hospitalization.
None.
Symptoms and signs associated with infection, with their time of evolution, specified in the study.
From 1005 eligible patients, 261 were included. After multivariable adjustment with a logistic regression model, the main factors for ICU admission or mortality were heart rate (OR 1.04 with 95% CI 1.04-3.7), respiratory rate (OR 1.19 with 95% CI 1.0-1.4) and capillary refill time (OR 3.4 with 95% CI 1.9-6.1).
Heart rate, respiratory rate, and capillary refill may behave as early predictors of ICU admission and mortality in cases of sepsis.
确定疑似感染或脓毒症患者的首发症状和体征及其与入住重症监护病房（ICU）或死亡的复合结局的关系。
2019 年 6 月至 2020 年 3 月进行的前瞻性队列研究。
哥伦比亚圣文森特基金会大学医院。
年龄在 18 岁以上，疑似或确诊为脓毒症，需要住院治疗。
无。
感染相关的症状和体征及其在研究中指定的演变时间。
在 1005 名符合条件的患者中，有 261 名患者被纳入研究。经过多变量逻辑回归模型调整后，入住 ICU 或死亡的主要因素有心律（OR 1.04，95%CI 1.04-3.7）、呼吸频率（OR 1.19，95%CI 1.0-1.4）和毛细血管再充盈时间（OR 3.4，95%CI 1.9-6.1）。
心率、呼吸频率和毛细血管再充盈时间可能是脓毒症患者入住 ICU 和死亡的早期预测指标。
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