腹腔镜下胃底折叠术伴瓣阀校准:一种安全有效的手术。

Laparoscopic floppy Nissen fundoplication with valve calibration: a safe and efficient procedure.

机构信息

Department of Digestive and Hepato-Pancreato-Biliary Surgery, Hôpital Saint Antoine, Assistance Publique Hôpitaux de Paris, 184 Rue du Faubourg Saint Antoine, 75012, Paris, France.

Sorbonne University, Paris, France.

出版信息

Surg Today. 2024 Sep;54(9):1041-1050. doi: 10.1007/s00595-024-02817-x. Epub 2024 Apr 8.

Abstract

PURPOSES

A floppy Nissen fundoplication with valve calibration (FNF-VC) performed by laparotomy has been described, to reduce postoperative dysphagia and gas bloating after 360°-fundoplication. As laparoscopy is the gold standard for fundoplication, this study reports the first results of a modified FNF-VC adapted for laparoscopy (LFNF).

METHODS

Seventy-two consecutive patients, who underwent LFNF for refractory GERD between 2012 and 2021, were included. Postoperative outcomes and quality of life (QoL) by GERSS, GERD-HRQL, and GIQLI scores before and after surgery were assessed.

RESULTS

The main symptoms were pyrosis (81%), regurgitation (39%), Ear-Nose-Throat symptoms (22%), and thoracic pain (24%). Hiatal hernia was present in 85% (n = 61) of the patients. There was no postoperative mortality, and the severe postoperative morbidity rate (Dindo-Clavien ≥ III) was 6%. After a median follow-up of 3.6 years, only 8% of patients were still taking proton-pump inhibitors. Long-term residual dysphagia was noted in 15% of the patients, but none required reoperation or interventional endoscopic procedures. QoL improved, with a significant reduction in GERSS and GERD-HRQL scores and a postoperative GIQLI of 101.75 (75-117.5).

CONCLUSION

This series reports the safety and efficacy of an FNF-VC adapted for laparoscopy to treat GERD with a limited rate of residual dysphagia.

摘要

目的

已描述通过剖腹手术进行的软式 Nissen 胃底折叠术伴瓣膜校准(FNF-VC),以减少 360°胃底折叠术后的术后吞咽困难和气体膨胀。由于腹腔镜检查是胃底折叠术的金标准,因此本研究报告了适应腹腔镜检查的改良 FNF-VC(LFNF)的首批结果。

方法

2012 年至 2021 年间,72 例连续接受 LFNF 治疗难治性 GERD 的患者被纳入本研究。评估术后结果和生活质量(通过 GERSS、GERD-HRQL 和 GIQLI 评分评估)。

结果

主要症状为烧心(81%)、反流(39%)、耳鼻咽喉症状(22%)和胸痛(24%)。85%(n=61)的患者存在食管裂孔疝。术后无死亡病例,严重术后发病率(Dindo-Clavien≥III)为 6%。中位随访 3.6 年后,仅 8%的患者仍在服用质子泵抑制剂。15%的患者长期存在残留吞咽困难,但均无需再次手术或介入内镜治疗。生活质量得到改善,GERSS 和 GERD-HRQL 评分显著降低,术后 GIQLI 为 101.75(75-117.5)。

结论

本系列报告了适应腹腔镜检查的 FNF-VC 治疗 GERD 的安全性和有效性,残留吞咽困难的发生率有限。

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