Healthy Aging North Dakota (HAND), North Dakota State University, Fargo, North Dakota.
Department of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, North Dakota.
J Strength Cond Res. 2024 Jul 1;38(7):e398-e404. doi: 10.1519/JSC.0000000000004780. Epub 2024 Apr 9.
McGrath, R, McGrath, BM, Jurivich, D, Knutson, P, Mastrud, M, Singh, B, and Tomkinson, GR. Collective weakness is associated with time to mortality in Americans. J Strength Cond Res 38(7): e398-e404, 2024-Using new weakness cutpoints individually may help estimate time to mortality, but their collective use could improve value. We sought to determine the associations of (a) each absolute and body size normalized cut point and (b) collective weakness on time to mortality in Americans. The analytic sample included 14,178 subjects aged ≥50 years from the 2006-2018 waves of the Health and Retirement Study. Date of death was confirmed from the National Death Index. Handgrip dynamometry measured handgrip strength (HGS). Men were categorized as weak if their HGS was <35.5 kg (absolute), <0.45 kg·kg -1 (body mass normalized), or <1.05 kg·kg -1 ·m -2 (body mass index [BMI] normalized). Women were classified as weak if their HGS was <20.0 kg, <0.337 kg·kg -1 , or <0.79 kg·kg -1 ·m -2 . Collective weakness categorized persons as below 1, 2, or all 3 cutpoints. Cox proportional hazard regression models were used for analyses. Subject values below each absolute and normalized cutpoint for the 3 weakness parameters had a higher hazard ratio for early all-cause mortality: 1.45 (95% confidence interval [CI]: 1.36-1.55) for absolute weakness, 1.39 (CI: 1.30-1.49) for BMI normalized weakness, and 1.33 (CI: 1.24-1.43) for body mass normalized weakness. Those below 1, 2, or all 3 weakness cut points had a 1.37 (CI: 1.26-1.50), 1.47 (CI: 1.35-1.61), and 1.69 (CI: 1.55-1.84) higher hazard for mortality, respectively. Weakness determined by a composite measure of absolute and body size adjusted strength capacity provides robust prediction of time to mortality, thus potentially informing sports medicine and health practitioner discussions about the importance of muscle strength during aging.
麦格拉思、R、麦格拉思、BM、朱里维奇、D、纳特森、P、马斯特鲁德、M、辛格、B 和汤姆金森、GR。美国人的集体虚弱与死亡率有关。J 力量与调理研究 38(7):e398-e404,2024-单独使用新的虚弱切点可能有助于估计死亡率，但它们的集体使用可能会提高价值。我们旨在确定（a）每个绝对和身体大小归一化切点和（b）美国人的集体虚弱与死亡率之间的关联。分析样本包括来自健康与退休研究 2006-2018 年各波的 14,178 名年龄≥50 岁的受试者。死亡日期从国家死亡指数中确认。手握力计测量握力（HGS）。如果男性的 HGS 小于 35.5 公斤（绝对）、小于 0.45 公斤·公斤 -1 （身体质量归一化）或小于 1.05 公斤·公斤 -1 ·米 -2 （身体质量指数[BMI]归一化），则将其归类为虚弱。如果女性的 HGS 小于 20.0 公斤、小于 0.337 公斤·公斤 -1 或小于 0.79 公斤·公斤 -1 ·米 -2 ，则将其分类为虚弱。集体虚弱将人分为低于 1、2 或所有 3 个切点。使用 Cox 比例风险回归模型进行分析。对于 3 个虚弱参数的每个绝对和归一化切点以下的受试者，全因早期死亡率的危险比更高：绝对虚弱为 1.45（95%置信区间[CI]：1.36-1.55）、BMI 归一化虚弱为 1.39（CI：1.30-1.49），身体质量归一化弱点为 1.33（CI：1.24-1.43）。低于 1、2 或所有 3 个弱点切点的受试者死亡率分别为 1.37（CI：1.26-1.50）、1.47（CI：1.35-1.61）和 1.69（CI：1.55-1.84）。由绝对和身体大小调整后的力量能力综合测量确定的弱点提供了对死亡率的有力预测，从而有可能为运动医学和健康从业者提供关于衰老过程中肌肉力量重要性的讨论。
