Yang Jae-Won, Park Mi-Ok
Gangnam Jaejun Plastic Clinic, Pyeongtaek-si, Gyeongi-do, Korea.
MioGreensumer Pathology Clinic, Incheon City, Korea.
Arch Plast Surg. 2024 Jan 24;51(2):196-201. doi: 10.1055/a-2222-1226. eCollection 2024 Mar.
Nevus lipomatosus superficialis (NLS) is a hamartoma of adipose tissue, rarely reported in the past 100 years. We treated one case, and we conducted a systematic review of the literature. A 41-year-old man presented with a cutaneous multinodular lesion in the posterior region near the right auricle. The lesion was excised and examined histopathologically. To review the literature, we searched PubMed with the keyword "NLS." The search was limited to articles written in English and whose full text was available. We analyzed the following data: year of report, nation of corresponding author, sex of patient, age at onset, duration of disease, location of lesion, type of lesion, associated symptoms, pathological findings, and treatment. Of 158 relevant articles in PubMed, 112 fulfilled our inclusion criteria; these referred to a total of 149 cases (cases with insufficient clinical information were excluded). In rare cases, the diagnosis of NLS was confirmed when the lesion coexisted with sebaceous trichofolliculoma and infestation. Clinical awareness for NLS has increased recently. NLS is an indolent and asymptomatic benign neoplasm that may exhibit malignant behavior in terms of huge lesion size and specific anatomical location. Early detection and curative treatment should be promoted.
浅表脂肪瘤样痣（NLS）是一种脂肪组织错构瘤，在过去100年中鲜有报道。我们治疗了1例，并对文献进行了系统回顾。一名41岁男性在右耳廓附近的后部区域出现皮肤多结节性病变。该病变被切除并进行了组织病理学检查。为回顾文献，我们在PubMed上以“NLS”为关键词进行搜索。搜索仅限于英文撰写且有全文的文章。我们分析了以下数据：报告年份、通讯作者所在国家、患者性别、发病年龄、病程、病变部位、病变类型、相关症状、病理结果和治疗方法。在PubMed上的158篇相关文章中，112篇符合我们的纳入标准；这些文章共提及149例病例（排除临床信息不足的病例）。在罕见情况下，当病变与皮脂腺毛囊瘤和感染共存时，可确诊为NLS。近年来，对NLS的临床认识有所提高。NLS是一种生长缓慢且无症状的良性肿瘤，在巨大病变尺寸和特定解剖位置方面可能表现出恶性行为。应促进早期发现和根治性治疗。
