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颈动脉内膜切除术(CEA)后颈内动脉远段支架置入术的紧急情况:适应证、技术和结果。

Bailout Distal Internal Carotid Artery Stenting after Carotid Endarterectomy: Indications, Technique, and Outcomes.

机构信息

Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

出版信息

Ann Vasc Surg. 2024 Aug;105:218-226. doi: 10.1016/j.avsg.2024.02.025. Epub 2024 Apr 8.

Abstract

BACKGROUND

Distal internal carotid artery (ICA) stenting may be employed as a bailout maneuver when an inadequate end point or clamp injury is encountered at the time of carotid endarterectomy (CEA) in a surgically inaccessible region of the distal ICA. We sought to characterize the indications, technique, and outcomes for this infrequently encountered clinical scenario.

METHODS

We performed a retrospective review of all patients who underwent distal ICA stenting at the time of CEA at our institution between September 2008 and July 2022. Procedural details and postoperative follow-up were reviewed for each patient.

RESULTS

Six patients were identified during the study period. All were male with an age range of 63 to 82 years. Five underwent carotid revascularization for asymptomatic carotid artery stenosis, and one patient was treated for amaurosis fugax. Three patients were on dual antiplatelet therapy preoperatively, whereas 2 were on aspirin monotherapy, and one was on aspirin and low-dose rivaroxaban. Five patients underwent CEA with patch angioplasty, and one underwent eversion CEA. The indication for stenting was distal ICA dissection due to clamp or shunt injury in 2 patients and an inadequate distal ICA end point in 4 patients. In all cases, access for stenting was obtained under direct visualization within the common carotid artery, and a standard carotid stent was deployed with its proximal aspect landing within the endarterectomized site. Embolic protection was typically achieved via proximal common carotid artery and external carotid artery clamping for flow arrest with aspiration of debris before restoration of antegrade flow. There was 100% technical success. Postoperatively, 2 patients were found to have a cranial nerve injury, likely occurring due to the need for high ICA exposure. Median length of stay was 2 days (range 1-7 days) with no instances of perioperative stroke or myocardial infarction. All patients were discharged on dual antiplatelet therapy with no further occurrence of stroke, carotid restenosis, or reintervention through a median follow-up of 17 months.

CONCLUSIONS

Distal ICA stenting is a useful adjunct in the setting of CEA complicated by inadequate end point or vessel dissection in a surgically inaccessible region of the ICA and can minimize the need for high-risk extensive distal dissection of the ICA in this situation.

摘要

背景

当在手术不可及的远端颈内动脉(ICA)区域进行颈动脉内膜切除术(CEA)时,遇到终点不理想或夹伤,可能会采用远端 ICA 支架置入术作为紧急抢救措施。我们旨在描述这种不常见临床情况下的适应证、技术和结果。

方法

我们对 2008 年 9 月至 2022 年 7 月期间在我院接受 CEA 时行远端 ICA 支架置入术的所有患者进行了回顾性分析。对每位患者的手术细节和术后随访情况进行了回顾。

结果

研究期间共确定了 6 例患者。所有患者均为男性,年龄 63 至 82 岁。5 例患者因无症状颈动脉狭窄行颈动脉血运重建,1 例患者因一过性黑矇就诊。术前 3 例患者接受双联抗血小板治疗,2 例患者接受阿司匹林单药治疗,1 例患者接受阿司匹林和低剂量利伐沙班治疗。5 例患者行 CEA 加补片成形术,1 例患者行外翻式 CEA。支架置入的适应证为 2 例因夹伤或分流伤导致的远端 ICA 夹层,4 例因远端 ICA 终点不理想。所有情况下,均在直视下通过颈总动脉获得支架置入入路,并将标准颈动脉支架置于内膜切除术部位内。通常通过颈总动脉和颈外动脉近端夹闭以实现栓塞保护,夹闭后暂停血流以抽吸碎屑,然后恢复顺行血流。支架置入技术均获得 100%成功。术后,2 例患者发现颅神经损伤,可能与需要高 ICA 显露有关。中位住院时间为 2 天(1-7 天),无围手术期卒中或心肌梗死发生。所有患者出院时均接受双联抗血小板治疗,中位随访 17 个月期间无卒中、颈动脉再狭窄或再次介入治疗发生。

结论

在 CEA 中遇到终点不理想或血管夹层时,若手术不可及的 ICA 区域存在复杂情况,远端 ICA 支架置入术是一种有用的辅助手段,可最大限度减少在此情况下对高危广泛 ICA 远端夹层的需求。

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