Gétaz E P, Shimaoka K
J Surg Oncol. 1979;12(2):181-9. doi: 10.1002/jso.2930120213.
Post-irradiation carcinoma of the thyroid is usually histologically well-differentiated. In general, those subjects who developed carcinoma had been exposed to low-to-moderate doses of irradiation for benign conditions. We reviewed the charts of 520 patients with Hodgkin's disease seen at Roswell Park Memorial Institute, and found 2 cases of anaplastic carcinoma amongst other thyroidal abnormalities. The existing reports of post-irradiation carcinoma are reviewed and suggestions are made for the management of heavily irradiated, potentially cured patients with Hodgkin's disease.
甲状腺放疗后癌通常在组织学上分化良好。一般来说，那些患癌的患者曾因良性疾病接受过低至中等剂量的放疗。我们回顾了罗斯威尔帕克纪念研究所诊治的520例霍奇金病患者的病历，发现在其他甲状腺异常中，有2例为间变性癌。本文回顾了现有的放疗后癌的报告，并对接受过大量放疗、有可能治愈的霍奇金病患者的管理提出了建议。
