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小儿高血脂症。

Pediatric hyperlipidemia.

机构信息

Department of Pediatric Cardiology, 4th Floor, Pediatric Superspeciality Wing Amrita Hospital, Sector 88, Faridabad, Haryana, 121002, India.

Department of Pediatric Cardiology, 4th Floor, Pediatric Superspeciality Wing Amrita Hospital, Sector 88, Faridabad, Haryana, 121002, India.

出版信息

Indian Heart J. 2024 Mar;76 Suppl 1(Suppl 1):S104-S107. doi: 10.1016/j.ihj.2023.11.269. Epub 2024 Apr 8.

Abstract

The leading cause of mortality worldwide is atherosclerotic cardiovascular disease. Atherosclerotic plaques are well known to originate early in the childhood. Identifying hyperlipidemia in early childhood creates an opportunity to prevent major cardiovascular events in adults. Children with identified risk factors are at an increased risk of developing cardiovascular incidents in later life. This article emphasizes the diagnosis and management of pediatric hyperlipidemia with reference to the recent guidelines. In terms of etiology pediatric hyperlipidemia are divided into primary and secondary causes. The mainstay of management includes high-risk target screening, early risk factor identification and lifestyle modifications in vulnerable population. Drug therapy is recommended in primary hyperlipidemia and in children with no response to lifestyle changes.

摘要

全球范围内导致死亡的主要原因是动脉粥样硬化性心血管疾病。众所周知,动脉粥样硬化斑块早在儿童期就开始形成。在儿童期发现血脂异常,为预防成年人心血管事件提供了机会。有明确危险因素的儿童在以后的生活中发生心血管事件的风险增加。本文参考最新指南,重点介绍了儿科血脂异常的诊断和管理。根据病因,儿科血脂异常分为原发性和继发性。管理的主要内容包括高危目标筛查、早期危险因素识别和脆弱人群的生活方式改变。原发性血脂异常和生活方式改变无反应的儿童推荐药物治疗。

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Clinical Practice Recommendations for Pediatric Dyslipidemia.儿科血脂异常临床实践建议。
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