Servicio de Anatomía Patológica, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
Servicio de Anatomía Patológica, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
Rev Esp Patol. 2024 Apr-Jun;57(2):120-122. doi: 10.1016/j.patol.2023.09.003. Epub 2024 Jan 10.
Some non-small cell carcinomas of the lung can express TTF1 and p40 in the same tumor cells. This event has been described in only six cases prior to this one, and only in one other female. It is an extraordinary event that appears as a new entity yet to be defined. The case presented is a woman with a non-small cell lung carcinoma with diffuse coexpression of TTF1 and p40 in the same cells.
一些肺的非小细胞癌在同一个肿瘤细胞中可以表达 TTF1 和 p40。在此之前,仅有 6 例病例和另一位女性病例中有过这种描述。这是一种罕见的事件,似乎是一种尚未确定的新实体。本文报道的病例为一名女性非小细胞肺癌患者,其肿瘤细胞中 TTF1 和 p40 弥漫共表达。