Cantú-Soriano Gonzalo Nathaniel, Padilla-Rodríguez Álvaro Lezid
DIGIPATH (Digital Pathology Laboratory), Escuela de Medicina Universidad Panamericana, Campus Ciudad de México, Ciudad de México, México.
DIGIPATH (Digital Pathology Laboratory), Escuela de Medicina Universidad Panamericana, Campus Ciudad de México, Escuela de Medicina Instituto Tecnológico y de Estudios Superiores de Monterrey, Campus Ciudad de México, Ciudad de México, México.
Rev Esp Patol. 2024 Apr-Jun;57(2):137-140. doi: 10.1016/j.patol.2023.11.003. Epub 2023 Dec 27.
Calcifying fibrous tumor (CFT) is a rare benign lesion of mesenchymal origin that may present similar characteristics to other more common tumors. We present the case of a 36-year-old woman with a tumor in the proximal jejunum, initially suspected to be a gastrointestinal stromal tumor (GIST). Surgical resection was performed, revealing a well-demarcated nodule at the anti-mesenteric border with microscopic features typical of a calcifying fibrous tumor. The tumor cells were positive for CD34 and negative for other markers, differentiating it from other neoplasms. Calcifying fibrous tumors can be confused with more common tumors because of its appearance, but an accurate diagnosis supported by immunohistochemistry is essential. Complete surgical excision is usually curative.
钙化性纤维性肿瘤(CFT)是一种罕见的间叶源性良性病变,可能具有与其他更常见肿瘤相似的特征。我们报告一例36岁女性,其空肠近端有一个肿瘤,最初怀疑是胃肠道间质瘤(GIST)。进行了手术切除,结果显示在系膜对侧缘有一个边界清晰的结节,具有钙化性纤维性肿瘤的典型微观特征。肿瘤细胞CD34呈阳性,其他标志物呈阴性,这使其与其他肿瘤相鉴别。钙化性纤维性肿瘤因其外观可能与更常见的肿瘤混淆,但免疫组织化学支持的准确诊断至关重要。完整的手术切除通常可治愈。