A case of agnogenic myeloid metaplasia evolving into acute myelogenous leukemia associated with the development of trisomy 11 in bone marrow cells.
作者信息
Dang C V, Stein P H, Gress D R, Dallabetta G A, Bender W L
出版信息
Am J Hematol. 1985 Jul;19(3):285-8. doi: 10.1002/ajh.2830190311.
PMID:3860004
Abstract
An 83-year-old woman who had a 5-year history of agnogenic myeloid metaplasia and a previous normal marrow cell karyotype presented with acute myelogenous leukemia (AML) associated with the development of trisomy 11 in 100% of cultured marrow cells. Isolated trisomy 11 in marrow cells has been reported previously in five cases of AML, suggesting that trisomy 11 is a nonrandom chromosomal aberration associated with AML.
摘要
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