Deschênes Sonya S, Nearchou Finiki, McInerney Amy, Schmitz Norbert, Pouwer Frans, Nouwen Arie
University College Dublin, Ireland.
University of Tübingen, Germany.
J Health Psychol. 2025 Apr;30(5):858-870. doi: 10.1177/13591053241243285. Epub 2024 Apr 10.
We examined the associations between childhood maltreatment and the risk of impaired glucose metabolism (IGM) or type 2 diabetes (T2D) in young adults aged 18-35. Participants ( = 8506) from the Lifelines Cohort Study without IGM or diabetes at baseline (2007-2013) were included. Childhood maltreatment was assessed by the Childhood Trauma Questionnaire (CTQ) and incident IGM/T2D was assessed by haemoglobin A levels (≥5.7%) in 2014-2017. There were 223 (2.6%) cases of IGM/T2D during the follow-up period. After adjusting for sociodemographic and health/lifestyle covariates and follow-up time, only the CTQ Sexual Abuse subscale was significantly associated with IGM/T2D (RR = 1.05 [95% CI = 1.01, 1.10]). The association remained when additionally accounting for depressive and anxiety symptoms (RR = 1.05 [95% CI = 1.00, 1.09]). Childhood sexual abuse was associated with an increased risk of IGM/T2D in young adults, highlighting the long-term metabolic consequences of childhood maltreatment.
我们研究了18至35岁年轻成年人中童年期受虐经历与葡萄糖代谢受损（IGM）或2型糖尿病（T2D）风险之间的关联。纳入了生命线队列研究中的参与者（n = 8506），这些参与者在基线期（2007 - 2013年）没有IGM或糖尿病。童年期受虐经历通过儿童创伤问卷（CTQ）进行评估，2014 - 2017年期间，新发IGM/T2D通过血红蛋白A水平（≥5.7%）进行评估。随访期间有223例（2.6%）IGM/T2D病例。在对社会人口统计学和健康/生活方式协变量以及随访时间进行调整后，只有CTQ性虐待分量表与IGM/T2D显著相关（风险比RR = 1.05 [95%置信区间CI = 1.01, 1.10]）。在进一步考虑抑郁和焦虑症状后，该关联仍然存在（RR = 1.05 [95% CI = 1.00, 1.09]）。童年期性虐待与年轻成年人中IGM/T2D风险增加相关，凸显了童年期受虐的长期代谢后果。
