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药物洗脱球囊在动脉循环系统中的研究进展

Research progress of drug eluting balloon in arterial circulatory system.

作者信息

Lu Keji, Ye Xianglin, Chen Yaoxuan, Wang Peng, Gong Meiting, Xuan Bing, Tang Zhaobing, Li Meiling, Hou Jun, Peng Ke, Pei Haifeng

机构信息

Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China.

School of Medical and Life Sciences, Chengdu University of TCM, Chengdu, China.

出版信息

Front Cardiovasc Med. 2024 Mar 20;11:1287852. doi: 10.3389/fcvm.2024.1287852. eCollection 2024.

Abstract

The arterial circulatory system diseases are common in clinical practice, and their treatment options have been of great interest due to their high morbidity and mortality. Drug-eluting balloons, as a new type of endovascular interventional treatment option, can avoid the long-term implantation of metal stents and is a new type of angioplasty without stents, so drug-eluting balloons have better therapeutic effects in some arterial circulatory diseases and have been initially used in clinical practice. In this review, we first describe the development, process, and mechanism of drug-eluting balloons. Then we summarize the current studies on the application of drug-eluting balloons in coronary artery lesions, in-stent restenosis, and peripheral vascular disease. As well as the technical difficulties and complications in the application of drug-eluting balloons and possible management options, in order to provide ideas and help for future in-depth studies and provide new strategies for the treatment of more arterial system diseases.

摘要

动脉循环系统疾病在临床实践中很常见,由于其高发病率和高死亡率,其治疗方案一直备受关注。药物洗脱球囊作为一种新型的血管内介入治疗选择,可以避免长期植入金属支架,是一种新型的无支架血管成形术,因此药物洗脱球囊在某些动脉循环疾病中具有更好的治疗效果,并已初步应用于临床实践。在这篇综述中,我们首先描述药物洗脱球囊的发展、过程和机制。然后我们总结了目前关于药物洗脱球囊在冠状动脉病变、支架内再狭窄和外周血管疾病中应用的研究。以及药物洗脱球囊应用中的技术难点和并发症以及可能的处理方法,以便为未来的深入研究提供思路和帮助,并为治疗更多动脉系统疾病提供新策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00fe/11005962/a60f75fc3349/fcvm-11-1287852-g001.jpg

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