Zsenák István, Makai Alexandra, Kiss Gabriella, Faludi Béla, Straub Alexandra, Szilágyi Brigitta, Velényi Anita, Járomi Melinda
Doctoral School of Health Sciences, University of Pécs, Pécs, Hungary.
Institute of Physiotherapy and Sport Science, University of Pécs Faculty of Health Sciences, Pécs, Hungary.
Front Physiol. 2024 Mar 27;15:1323840. doi: 10.3389/fphys.2024.1323840. eCollection 2024.
Studies have shown that using mechanical thromboembolic prophylaxis methods speeds up venous flow and decreases stasis. These studies examine the post-intervention period of 1-10 min. The length of the effect of procedures to raise venous flow velocity cannot be determined by clinical trials. To apply mathematical techniques to estimate how long mechanical thromboembolism prophylaxis procedures will increase venous flow rate.
In the survey, we examined 25 persons (poststroke patients), with an average age of 57.2 ± 6.3 years. Regarding the proportion of genders, 13 (52%) participants were male and 12 (48%) female. The peak venous blood flow velocity was measured with a HADECO BIDOP ES-100V II type Doppler ultrasound device, using an 8 MHz head, in the femoral vein, at the level of the hip joint. We estimated the change of the venous blood flow velocity from the available sampled data using the method of least squares. For the calculations, we used Microsoft Excel, version Mac Excel 2019.
The decrease in peak venous flow velocity can be approximated by a logarithm function. Mathematical calculations show that after active thromboembolic prophylaxis interventions, resting venous flow velocity is restored at 26.8 min on the intact limb and 85.1 min on the hemiparetic side. Resting flow velocity is restored in 131.9 min after passive mobilization of the hemiparetic side and in 137.7 min after the consensual effect.
An elementary mathematical function can be used to estimate the time to recovery of peak venous flow velocity to resting state from measurements taken 15 min after the intervention. Active and passive mechanical thromboembolic prophylaxis after the intervention has a longer-term effect on venous flow velocity.
研究表明,使用机械性血栓栓塞预防方法可加快静脉血流并减少血液淤滞。这些研究考察的是干预后1至10分钟的时间段。临床试验无法确定提高静脉血流速度的程序的效果持续时长。应用数学技术来估计机械性血栓栓塞预防程序会使静脉血流速度增加多长时间。
在这项调查中,我们检查了25名(中风后患者),平均年龄为57.2±6.3岁。在性别比例方面,13名(52%)参与者为男性,12名(48%)为女性。使用HADECO BIDOP ES - 100V II型多普勒超声设备,配备8MHz探头,在髋关节水平的股静脉处测量静脉血流峰值速度。我们使用最小二乘法从可用的采样数据中估计静脉血流速度的变化。计算时,我们使用了Microsoft Excel,Mac Excel 2019版本。
静脉血流峰值速度的下降可用对数函数近似。数学计算表明,在进行积极的血栓栓塞预防干预后,健侧肢体静息静脉血流速度在26.8分钟恢复,偏瘫侧在85.1分钟恢复。偏瘫侧被动活动后静息血流速度在131.9分钟恢复,在协同效应后137.7分钟恢复。
一个基本的数学函数可用于从干预后15分钟所测数据估计静脉血流峰值速度恢复到静息状态的时间。干预后的主动和被动机械性血栓栓塞预防对静脉血流速度有更长期的影响。