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左环指复发性局限性腱鞘巨细胞瘤:病例报告及文献综述

Recurrent Localized Tenosynovial Giant Cell Tumor of the Left Ring Finger: A Case Report and Literature Review.

作者信息

Awosusi Babatope L, Attia Omar M

机构信息

Pathology and Laboratory Medicine, King Khalid Hospital, AlMajmaah, SAU.

Plastic Surgery, King Khalid Hospital, AlMajmaah, SAU.

出版信息

Cureus. 2024 Mar 11;16(3):e55962. doi: 10.7759/cureus.55962. eCollection 2024 Mar.

Abstract

Here, we report the case of recurrent swelling and pain in the proximal interphalangeal joint of the left ring finger, which was later diagnosed as a localized tenosynovial giant cell tumor in a young adult female. The first presentation was at the same anatomical site four years prior. Examination at presentation showed a firm skin-colored nodule in the volar aspect of the left ring finger. The swelling was seen to be partly attached to underlying structures and was non-tender. After a careful physical examination and plain radiograph imaging of the hand, the two differential diagnoses considered were tenosynovial giant cell tumor and ganglion cyst. A surgical excision was performed, and histopathologic evaluation showed features consistent with a tenosynovial giant cell tumor, localized type. The resection margins were clear of tumor. The patient had no intraoperative or postoperative complications. Postoperative physiotherapy was recommended. No recurrence was seen after postoperative surgical follow-up for one year. This report highlights the importance of histopathologic evaluation and confirmation of clear surgical margins in the management of tenosynovial giant cell tumors. In recurrent cases, surgical re-excision with clear margins provides good clinical outcomes. Before surgical excision, patients should be informed about the biologic nature of the lesion and the high risk of recurrence. The management modalities to prevent recurrence and the need for long-term follow-up should also be discussed with the patient.

摘要

在此,我们报告一例年轻成年女性左环指近端指间关节反复肿胀和疼痛的病例,该病例后来被诊断为局限性腱鞘巨细胞瘤。首次出现症状是在四年前的同一解剖部位。就诊时检查发现左环指掌侧有一个质地硬、肤色的结节。肿胀部分与深层结构相连,无压痛。经过仔细的体格检查和手部X线平片成像后,考虑的两个鉴别诊断是腱鞘巨细胞瘤和腱鞘囊肿。进行了手术切除,组织病理学评估显示其特征符合局限性腱鞘巨细胞瘤。切除边缘无肿瘤。患者无术中或术后并发症。建议术后进行物理治疗。术后随访一年未见复发。本报告强调了组织病理学评估以及在腱鞘巨细胞瘤治疗中确认手术切缘清晰的重要性。对于复发病例,进行切缘清晰的再次手术切除可取得良好的临床效果。在手术切除前,应告知患者病变的生物学性质以及复发的高风险。还应与患者讨论预防复发的管理方式以及长期随访的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7518/11006002/288742d44589/cureus-0016-00000055962-i01.jpg

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