Subramanian R V
Ann N Y Acad Sci. 1985;446:134-48. doi: 10.1111/j.1749-6632.1985.tb18396.x.
The synthesis, structure, and properties of polymers in which tin is chemically anchored as tributyltin carboxylate are discussed. A base copolymer with anhydride or carboxyl groups is partially esterified with tributyltin oxide; the free carboxyls are then reacted with diepoxides to yield cross-linked controlled release formulations. The network structure and the separation length and type of epoxide cross-links were altered by changing the degree of esterification of the base polymer, the structure of epoxy monomer, and catalyst. NMR evidence established that rapid exchange exists in tributyltin carboxylates; as a consequence even their interfacial reaction with chloride is fast, producing tributyltin chloride. Biotoxicity data obtained by studying the inhibition of marine and soil bacteria reveal that the type and degree of cross-linking have a significant effect on the size of inhibition zones. Tests in the ocean confirm effective biological activity against marine fouling organisms. Structural correlations with dynamic mechanical and dielectric properties suggest a viable program to investigate the dependence of tributyltin release on polymer matrix properties.
讨论了锡作为羧酸三丁基锡化学锚定在其中的聚合物的合成、结构和性能。带有酸酐或羧基的基础共聚物用氧化三丁基锡进行部分酯化；然后使游离羧基与二环氧化物反应，以得到交联控释制剂。通过改变基础聚合物的酯化程度、环氧单体的结构和催化剂，改变了网络结构以及环氧交联的分离长度和类型。核磁共振证据表明，羧酸三丁基锡中存在快速交换；因此，即使它们与氯化物的界面反应也很快，生成氯化三丁基锡。通过研究对海洋和土壤细菌的抑制作用获得的生物毒性数据表明，交联的类型和程度对抑菌圈大小有显著影响。在海洋中的测试证实了对海洋污损生物具有有效的生物活性。与动态力学和介电性能的结构相关性表明了一个可行的方案，以研究三丁基锡释放对聚合物基体性能的依赖性。
