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新冠后抑郁、反复发热和皮肤损伤的高剂量锂治疗病例报告。

Case Report on High Dose Lithium Treatment for Post-COVID Depression, Recurrent Fevers, and Skin Lesions.

机构信息

Massoumi, MD, Michigan State University, Integrative Psychiatry Services, PC, Bingham Farms, MI.

Rosenbaum, MD, Wayne State University, West Bloomfield, MI.

出版信息

Psychopharmacol Bull. 2024 Apr 4;54(2):39-45.

PMID:38601833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11003256/
Abstract

This is a case of a 35-year-old woman who presented with an 18-month history of post (long)-COVID depression and exhaustion along with recurrent fevers and treatment-resistant skin boils, all of which abated with lithium treatment at a serum level of 1.14 mmol/L, and all of which worsened when the lithium serum level was lowered to 0.8. This paper illustrates Lithium's effectiveness in the treatment of post (long)-COVID syndrome, though a higher serum concentration may be required.

摘要

这是一位 35 岁女性的病例,她因长新冠后抑郁和疲惫,以及反复发作的发热和对抗生素治疗无效的皮肤疖而就诊。这些症状在血清锂水平为 1.14mmol/L 时用锂治疗后缓解,而当血清锂水平降低至 0.8mmol/L 时则恶化。本文说明了锂在治疗长新冠综合征中的有效性,尽管可能需要更高的血清浓度。

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本文引用的文献

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Peripheral cytokine levels across psychiatric disorders: A systematic review and network meta-analysis.精神障碍患者外周细胞因子水平:系统评价和网络荟萃分析。
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Differences in the Course of Depression and Anxiety after COVID-19 Infection between Recovered Patients with and without a Psychiatric History: A Cross-Sectional Study.新冠肺炎感染后,有和无精神病史的康复患者抑郁和焦虑病程的差异:一项横断面研究。
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Time to Stop Using Ineffective Covid-19 Drugs.是时候停止使用无效的新冠病毒药物了。
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Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19.二甲双胍、伊维菌素和氟伏沙明治疗 COVID-19 的随机试验。
N Engl J Med. 2022 Aug 18;387(7):599-610. doi: 10.1056/NEJMoa2201662.
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Associations of Depression, Anxiety, Worry, Perceived Stress, and Loneliness Prior to Infection With Risk of Post-COVID-19 Conditions.感染新冠病毒前的抑郁、焦虑、担忧、感知压力和孤独感与新冠后疾病风险的关联。
JAMA Psychiatry. 2022 Nov 1;79(11):1081-1091. doi: 10.1001/jamapsychiatry.2022.2640.
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C-reactive protein could predict the efficacy of SSRIs in clinical practice: A cohort study of large samples in the real world.C 反应蛋白可预测 SSRI 在临床实践中的疗效:真实世界大样本队列研究。
J Affect Disord. 2022 Sep 15;313:251-259. doi: 10.1016/j.jad.2022.06.080. Epub 2022 Jun 27.
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Efficacy and Safety of Lithium Treatment in SARS-CoV-2 Infected Patients.锂治疗对新冠病毒感染患者的疗效与安全性
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Lithium salts as a treatment for COVID-19: Pre-clinical outcomes.锂盐治疗 COVID-19:临床前结果。
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Br J Psychiatry. 2022 Jul;221(1):425-427. doi: 10.1192/bjp.2022.42.
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Lancet Infect Dis. 2022 Apr;22(4):e102-e107. doi: 10.1016/S1473-3099(21)00703-9. Epub 2021 Dec 21.