Karapapak Murat, Olgun Ali
Department of Ophthalmology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Department of Ophthalmology, West Eye Hospital, Erbil, Iraq.
Eur J Ophthalmol. 2024 Sep;34(5):1489-1496. doi: 10.1177/11206721241247440. Epub 2024 Apr 11.
To compare the efficacy of gonioscopy-assisted transluminal trabeculotomy (GATT) versus micropulse transscleral diode laser cyclophotocoagulation(MP-TDLC) combined with GATT in the treatment of advanced glaucoma.
This retrospective comparative study study included 82 patients (82 eyes) with a diagnosis of advanced glaucoma: 36 patients underwent GATT, and 46 underwent GATT + MP-TDLC. Intraocular pressure (IOP) changes in patients who underwent GATT and GATT MP-TDLC were analyzed retrospectively at regular intervals during the 6-month follow-up period.
For the 82 patients included in this study, the mean ± SD IOPs before the procedures were 27.2 ± 8.5 mmHg in the GATT group and 26.6 ± 6.9 mmHg in the GATT + MP-TDLC group ( = 0.866), and the numbers of glaucoma medications used were 3.41 ± 0.5 in the GATT group and 3.36 ± 0.4 in the GATT + MP-TDLC group ( = 0.605). The mean IOP after GATT was 13.6 ± 3.9 mmHg at day 1, 13.9 ± 3.7 mmHg at week 1, 14.6 ± 4.0 mmHg at month 1, 15.3 ± 4.3 mmHg at month 3, and 14.7 ± 3.3 mmHg at month 6. In the GATT + MP-TDLC group, the postoperative day 1, week 1, month 1, month 3, and month 6 IOP values were 12.4 ± 2.5, 11.8 ± 1.8, 12.1 ± 2.0, 11.8 ± 1.09, and 11.8 ± 1.5 mmHg, respectively.
GATT was found to be effective in the treatment of patients with advanced glaucoma, and results closer to the targeted low teens IOP values were obtained with GATT + MP-TDLC.
比较房角镜辅助小梁切开术（GATT）与微脉冲经巩膜二极管激光睫状体光凝术（MP-TDLC）联合GATT治疗晚期青光眼的疗效。
这项回顾性比较研究纳入了82例（82只眼）诊断为晚期青光眼的患者：36例接受了GATT，46例接受了GATT + MP-TDLC。在6个月的随访期内定期回顾性分析接受GATT和GATT + MP-TDLC患者的眼压（IOP）变化。
本研究纳入的82例患者中，GATT组术前平均±标准差眼压为27.2±8.5 mmHg，GATT + MP-TDLC组为26.6±6.9 mmHg（P = 0.866），GATT组使用的青光眼药物数量为3.41±0.5，GATT + MP-TDLC组为3.36±0.4（P = 0.605）。GATT术后第1天眼压为13.6±3.9 mmHg，第1周为13.9±3.7 mmHg，第1个月为14.6±4.0 mmHg，第3个月为15.3±4.3 mmHg，第6个月为14.7±3.3 mmHg。在GATT + MP-TDLC组中，术后第1天、第1周、第1个月、第3个月和第6个月的眼压值分别为12.4±2.5、11.8±1.8、12.1±2.0、11.8±1.09和11.8±1.5 mmHg。
发现GATT对晚期青光眼患者有效，GATT + MP-TDLC能获得更接近目标眼压值低至十几mmHg的结果。
