Burn Rehabilitation Department, Regional One Health, Memphis, TN 38103, USA.
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
J Burn Care Res. 2024 Aug 6;45(4):822-827. doi: 10.1093/jbcr/irae060.
Cultured epidermal autografts (CEA) have since become more prevalent in the treatment of burn-injured patients with limited available donor sites for adequate wound closure, resulting in decreased mortality rates and an increased number of these patients requiring burn therapy services to achieve optimal functional outcomes at discharge. However, the use and postoperative management of CEA continue to be controversial due large to the physiological fragility and expense of CEA, leading to variable postoperative treatment practices across burn centers. As such, minimal research is available regarding patient outcomes following CEA application, specifically related to burn therapy intervention. Thus, a retrospective chart review was conducted on a series of 10 patients, 18 years of age or older, admitted to a single, American Burn Association verified burn center, between April 2015 and April 2023, who required CEA and received pre- and postoperative treatment by burn therapists in accordance with center-specific burn rehabilitation guidelines. The resulting patient outcomes, in response to early implementation of therapy interventions post-CEA surgery, demonstrated optimal functional status for patients upon discharge and positive long-term implications.
培养的表皮自体移植物（CEA）在治疗烧伤患者中越来越流行，这些患者的供体部位有限，无法充分闭合伤口，从而降低了死亡率，并且需要烧伤治疗服务的患者数量增加，以实现出院时的最佳功能结果。然而，由于 CEA 的生理脆弱性和昂贵性，CEA 的使用和术后管理仍然存在争议，导致烧伤中心之间的术后治疗实践存在差异。因此，关于 CEA 应用后患者的结果，特别是与烧伤治疗干预相关的研究很少。因此，对 2015 年 4 月至 2023 年 4 月期间入住一家美国烧伤协会认证的烧伤中心的 10 名年龄在 18 岁及以上的患者进行了回顾性图表审查，这些患者需要 CEA，并按照中心特定的烧伤康复指南，由烧伤治疗师进行术前和术后治疗。对 CEA 手术后早期实施治疗干预的患者的结果进行分析，结果表明，患者出院时的功能状态最佳，长期效果积极。
