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不修剪穿孔边缘的软骨鼓膜成形术后的移植物愈合过程

Graft Healing Process Following Cartilage Myringoplasty Without Trimming of the Perforation Margin.

作者信息

Wu Meixia, Lou Zhengcai

机构信息

Central Sterile Supply Department, Yiwu Central Hospital, Jinhua, Zhejiang, China.

Department of Otorhinolaryngology, Wenzhou Medical University Affiliated Yiwu Hospital, Yiwu, Zhejiang, China.

出版信息

Ear Nose Throat J. 2024 Apr 11:1455613241245210. doi: 10.1177/01455613241245210.

Abstract

The objective of this study was to endoscopically evaluate the graft healing process and graft success rate following cartilage myringoplasty, without trimming of the perforation margin or external ear canal (EAC) packing. Patients with chronic tympanic membrane (TM) perforation underwent endoscope cartilage underlay myringoplasty, without trimming perforation margin or EAC packing. The healing process of the cartilage graft and the graft success rate were evaluated at 6 months postoperatively. Fifty-eight ears were included in this study. At 1 week postoperatively, clinical inosculation and neovascularization of the graft were observed in small- and medium-sized perforations, but not in large or subtotal perforations. At 2 weeks postoperatively, graft clinical inosculation and neovascularization were completed in the small- and medium-sized perforations; however, neovascularization of the graft had only just begun in the large perforations. At 3 weeks postoperatively, completion of the graft clinical inosculation was achieved in 57 of the 58 ears. At 4 weeks postoperatively, complete neovascularization was achieved in all perforations. Of the 58 ears, postoperative infection resulted in residual perforation in 1 ear, and an insufficient graft resulted in residual perforation in a large perforation without infection. Overall, the graft success rate was 96.6% (56/58). There was no correlation between the graft success rate and graft neovascularization score. The graft healing process experienced the dilation of the blood vessels of the remnant TM, graft clinical inosculation, and neovascularization following cartilage myringoplasty without trimming of the perforation margin and EAC packing; however, the graft success rate was not related to the endoscopic graft neovascularization scores.

摘要

本研究的目的是在内窥镜下评估软骨鼓膜成形术后移植物的愈合过程和移植物成功率,不修剪穿孔边缘或不对外耳道(EAC)进行填塞。慢性鼓膜(TM)穿孔患者接受了内窥镜下软骨衬里鼓膜成形术,不修剪穿孔边缘或不对外耳道进行填塞。在术后6个月评估软骨移植物的愈合过程和移植物成功率。本研究纳入了58只耳朵。术后1周,在中小穿孔中观察到移植物的临床愈合和新生血管形成,但在大穿孔或次全穿孔中未观察到。术后2周,中小穿孔中移植物的临床愈合和新生血管形成完成;然而,大穿孔中移植物的新生血管形成才刚刚开始。术后3周,58只耳朵中有57只实现了移植物的临床愈合。术后4周,所有穿孔均实现了完全新生血管形成。在这58只耳朵中,术后感染导致1只耳朵出现残余穿孔,移植物不足导致1只无感染的大穿孔出现残余穿孔。总体而言,移植物成功率为96.6%(56/58)。移植物成功率与移植物新生血管形成评分之间无相关性。在不修剪穿孔边缘和不对外耳道进行填塞的软骨鼓膜成形术后,移植物的愈合过程经历了残余鼓膜血管扩张、移植物临床愈合和新生血管形成;然而,移植物成功率与内窥镜下移植物新生血管形成评分无关。

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