Salvador Renato, Pandolfino John E, Costantini Mario, Gyawali Chandra Prakash, Keller Jutta, Mittal Sumeet, Roman Sabine, Savarino Edoardo V, Tatum Roger, Tolone Salvatore, Zerbib Frank, Capovilla Giovanni, Jain Anand, Kathpalia Priya, Provenzano Luca, Yadlapati Rena
Department of Surgical, Oncological, and Gastroenterological Sciences, University of Padua, School of Medicine, Padova, Italy.
Division of Gastroenterology, Northwestern University, Chicago, IL.
Ann Surg. 2025 Jan 1;281(1):124-135. doi: 10.1097/SLA.0000000000006297. Epub 2024 Apr 12.
In the last 2 decades the development of high-resolution manometry (HRM) has changed and revolutionized the diagnostic assessment of patients complain foregut symptoms. The role of HRM before and after antireflux procedure remains unclear, especially in surgical practice, where a clear understanding of esophageal physiology and hiatus anatomy is essential for optimal outcome of antireflux surgery (ARS). Surgeons and gastroenterologists (GIs) agree that assessing patients following antireflux procedures can be challenging. Although endoscopy and barium-swallow can reveal anatomic abnormalities, physiological information on HRM allowing insight into the cause of eventually recurrent symptoms could be key to clinical decision-making.
A multidisciplinary international working group (14 surgeons and 15 GIs) collaborated to develop consensus on the role of HRM pre-ARS and post-ARS, and to develop a postoperative classification to interpret HRM findings. The method utilized was detailed literature review to develop statements, and the RAND/University of California, Los Angeles Appropriateness Methodology (RAM) to assess agreement with the statements. Only statements with an approval rate >80% or a final ranking with a median score of 7 were accepted in the consensus. The working groups evaluated the role of HRM before ARS and the role of HRM following ARS.
This international initiative developed by surgeons and GIs together, summarizes the state of our knowledge of the use of HRM pre-ARS and post-ARS. The Padova Classification was developed to facilitate the interpretation of HRM studies of patients underwent ARS.
在过去20年中,高分辨率测压法(HRM)的发展改变并彻底革新了对有前肠症状患者的诊断评估。抗反流手术前后HRM的作用仍不明确,尤其是在外科手术实践中,清楚了解食管生理和裂孔解剖对于抗反流手术(ARS)的最佳效果至关重要。外科医生和胃肠病学家一致认为,评估抗反流手术后的患者具有挑战性。虽然内镜检查和吞钡检查可以发现解剖学异常,但HRM提供的生理信息有助于深入了解最终复发症状的原因,这可能是临床决策的关键。
一个多学科国际工作组(14名外科医生和15名胃肠病学家)合作,就ARS术前和术后HRM的作用达成共识,并制定术后分类以解释HRM结果。采用的方法是详细的文献综述以形成陈述,并使用兰德/加利福尼亚大学洛杉矶分校适宜性方法(RAM)来评估对这些陈述的认同度。只有批准率>80%或最终排名中位数得分≥7的陈述才被纳入共识。工作组评估了ARS术前HRM的作用以及ARS术后HRM的作用。
由外科医生和胃肠病学家共同发起的这项国际倡议,总结了我们对ARS术前和术后使用HRM的认识状况。帕多瓦分类法的制定是为了便于解释接受ARS患者的HRM研究结果。