Zhang Xinyu, Cai Xin, Yin Naiqiang, Wang Yingying, Jiao Yang, Liu Chundong
School of Physics and Electronic Engineering, Qilu Normal University, Jinan 250200, China.
School of Physics and Electronics, Shandong Normal University, Jinan 250014, China.
Nanomaterials (Basel). 2024 Mar 25;14(7):566. doi: 10.3390/nano14070566.
Surface-enhanced Raman scattering (SERS), as one of the most powerful analytical methods, undertakes important inspection tasks in various fields. Generally, the performance of an SERS-active substrate relies heavily on its structure, which makes it difficult to integrate multiple-functional detectability on the same substrate. To address this problem, here we designed and constructed a film of graphene/Au nanoparticles (G/Au film) through a simple method, which can be conveniently transferred to different substrates to form various composite SERS substrates subsequently. By means of the combination of the electromagnetic enhancement mechanism (EM) and the chemical enhancement mechanism (CM) of this structure, the film realized good SERS performance experimentally, with the enhancement factor (EF) approaching ca. 1.40 × 10. In addition, the G/Au film had high mechanical strength and had large specific surface area and good biocompatibility that is beneficial for Raman detection. By further transferring the film to an Ag/Si composite substrate and PDMS flexible film, it showed enhanced sensitivity and in situ detectability, respectively, indicating high compatibility and promising prospect in Raman detection.
表面增强拉曼散射（SERS）作为最强大的分析方法之一，在各个领域承担着重要的检测任务。一般来说，SERS活性基底的性能在很大程度上依赖于其结构，这使得在同一基底上集成多功能检测能力变得困难。为了解决这个问题，我们在此通过一种简单的方法设计并构建了一种石墨烯/金纳米颗粒薄膜（G/Au薄膜），随后它可以方便地转移到不同的基底上以形成各种复合SERS基底。借助这种结构的电磁增强机制（EM）和化学增强机制（CM）的结合，该薄膜在实验中实现了良好的SERS性能，增强因子（EF）接近约1.40×10。此外，G/Au薄膜具有高机械强度、大比表面积以及良好的生物相容性，这有利于拉曼检测。通过进一步将该薄膜转移到Ag/Si复合基底和聚二甲基硅氧烷（PDMS）柔性薄膜上，它分别表现出增强的灵敏度和原位检测能力，表明其在拉曼检测中具有高兼容性和广阔的前景。
