Department of Medical Retina and Uvea, Prabha Eye Clinic, Bangalore, India.
Department of Vitreo-Retina, Vittala International Institute of Ophthalmology, Bangalore, India.
Ocul Immunol Inflamm. 2024 Oct;32(8):1609-1613. doi: 10.1080/09273948.2023.2268195. Epub 2024 Apr 12.
To document vascular changes in eyes with post-fever retinitis (PFR) pre and post treatment demonstrated using optical coherence tomography angiography (OCTA).
This is a retrospective observational case series wherein patients with PFR were retrospectively evaluated for changes in the retinal vasculature during the course of disease using OCTA.
At presentation, OCTA revealed flow void areas in superficial and deep capillary plexus (SCP and DCP) corresponding to the areas of retinitis. Post treatment, OCTA showed a significant decrease in the flow void areas with the appearance of new capillary network in both SCP and DCP. The optical coherence tomography also demonstrated normalization of retinal architecture over time. It is speculated that the good visual outcome in PFR could be attributed to the normalization of retinal architecture and remodelling in retinal vasculature.
OCTA being non-invasive can be used to understand and quantify the extent of vascular remodelling in PFR.
通过光相干断层扫描血管造影术（OCTA），记录发热后视网膜病变（PFR）患者治疗前后眼部血管变化。
本研究为回顾性观察性病例系列研究，对 PFR 患者的视网膜血管疾病过程中使用 OCTA 进行回顾性评估。
在就诊时，OCTA 显示与视网膜病变相对应的浅层和深层毛细血管丛（SCP 和 DCP）中出现血流空区。治疗后，OCTA 显示血流空区明显减少，SCP 和 DCP 中出现新的毛细血管网。光学相干断层扫描还显示视网膜结构随时间的恢复正常。据推测，PFR 良好的视力结果可能归因于视网膜结构和视网膜血管重塑的正常化。
OCTA 为非侵入性检查，可以用于了解和量化 PFR 中血管重塑的程度。
