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酮咯酸注射剂在肌肉骨骼疾病中的应用:一篇叙述性综述。

Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review.

机构信息

Department of Emergency Medicine, University of Florida, Jacksonville, Florida.

Department of Sports Medicine, University of Florida, Jacksonville, Florida.

出版信息

Clin Med Res. 2024 Mar;22(1):19-27. doi: 10.3121/cmr.2024.1847.

Abstract

Musculoskeletal conditions of the upper and lower extremities are commonly treated with corticosteroid injections. Ketorolac, a parenteral nonsteroidal anti-inflammatory drug, represents an alternative injectant for common shoulder, hip, and knee conditions. A review of the current literature was conducted on the efficacy of ketorolac injection in musculoskeletal diseases. Several studies support the use and efficacy of ketorolac injection in subacromial bursitis, adhesive capsulitis, and hip and knee osteoarthritis. Given the systemic effects of glucocorticoid injections, ketorolac may be a safe and effective alternative in patients with musculoskeletal disease. However, more evidence is required to better understand the effects ketorolac has on the human body during inflammatory processes.

摘要

四肢的肌肉骨骼疾病通常采用皮质类固醇注射治疗。酮咯酸,一种注射用的非甾体类抗炎药,为常见的肩部、髋部和膝部疾病提供了另一种注射选择。对酮咯酸注射治疗肌肉骨骼疾病的疗效的现有文献进行了综述。几项研究支持酮咯酸注射治疗肩峰下滑囊炎、粘连性囊炎和髋、膝关节骨关节炎的使用和疗效。鉴于糖皮质激素注射的全身作用,酮咯酸可能是肌肉骨骼疾病患者的一种安全有效的替代药物。然而,需要更多的证据来更好地了解酮咯酸在炎症过程中对人体的影响。

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